Auchenorrhyncha (planthoppers and leafhoppers) are herbivorous organisms that can ingest Cry proteins from genetically engineered Bt-crops depending on their feeding behaviour. Consequently, they might be directly affected by non-target Bt-protein action and more importantly serve as a source of Cry protein exposure to beneficial predatory arthropods. During a three year field study, we surveye...

To produce an in vitro model of nemaline myopathy, we reprogrammed the peripheral blood mononuclear cells (PBMCs) a patient with heterozygous p.Gly148Asp mutation exon 3 ACTA1 gene to iPSCs. Using CRISPR/Cas9 editing corrected generate isogenic control line. Both mutant and show normal karyotype, express pluripotency markers could differentiae into three cell states that represent embryonic ger...

Midkine is a secreted protein that acts as growth factor or cytokine involved in cell survival and inflammatory processes. It accumulates amyloid plaques, which are hallmarks of Alzheimer’s Disease (AD). The reproducibility Midkine research would be enhanced if the community had access to well-characterized anti-Midkine antibodies. In this study, we characterized 8 commercial antibodies ...

Skin and soft-tissue infections (SSTIs) caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) have emerged as major health problems throughout the world. Most SSTI CA-MRSA strains produce Panton-Valentine leukocidin (PVL), but its contribution to CA-MRSA pathogenesis is poorly defined. Here, we used an endemic PVL-positive SSTI-causing CA-MRSA strain from Taiwan, ...

In order to look into the genetic basis of intervarietal F(1) sterility in rice (Oryza sativa L.), a series of backcrosses (up to B(13)) was carried out using Taichung 65 (Japonica type) as the recurrent parent and several Indica varieties as donor parents. A number of "isogenic F(1)-sterile lines" were isolated by test-crossing fertile F(2) plants obtained from the selfing of partly pollenster...