Curiosity is an emotional motivation that drives knowledge acquisition in learning context. Studies have shown that curiosity positively influences social learning and a peer learner’s curiosity may elicit the curiosity of other learners. Hence, modeling curiosity in learning companions may improve human learners’ learning experience in virtual environments. However, curiosity has not been expl...

A second generation mutant of dimeric human pancreas RNase (HHP2-RNase), was obtained by a single residue mutation (Glu(111)-->Gly) of the previously described dimeric human pancreas RNase variant (HHP-RNase). HHP2-RNase was found to be a highly specific antitumour agent, with an enhanced cytotoxic activity compared with HHP-RNase. The structural and functional requisites of the antitumour acti...

Assistant Supervisor: Dott.ssa Giorgia Lodi ii iii to my family and my long-time and more recent friends iv Acknowledgements I believe that one's results heavily depend on the context he lives daily. Looking back to my life and to the goals I've accomplished, I consider myself very lucky to have been surrounded by persons that have always given me the required serenity and the right boost to go...

Silvia A Arredondo, Tiffany F Chen, Austen F. Riggs, Hiram F Gilbert*, and George Georgiou 2, 3, 4 Departments of Chemical Engineering Biomedical Engineering, Molecular Genetics and Microbiology, Institute for Cell and Molecular Biology and Section of Neurobiology, School of Biological Sciences, University of Texas, Austin, TX 78712; and *Department of Biochemistry, Baylor College of Medicine, ...

Authors/Task Force Members: Kenneth Dickstein (Chairperson) (Norway)*, Alain Cohen-Solal (France), Gerasimos Filippatos (Greece), John J.V. McMurray (UK), Piotr Ponikowski (Poland), Philip Alexander Poole-Wilson (UK), Anna Strömberg (Sweden), Dirk J. van Veldhuisen (The Netherlands), Dan Atar (Norway), Arno W. Hoes (The Netherlands), Andre Keren (Israel), Alexandre Mebazaa (France), Markku Niem...

Four crystalline, porous metal-organic frameworks (MOFs), based on a new hexatopic linker, 1',2',3',4',5',6'-hexakis(4-carboxyphenyl)benzene (H6CPB), were synthesized and fully characterized. Interestingly, two members of this series exhibited new topologies, namely, htp and hhp, which were previously unseen in MOF chemistry. Gas adsorption measurements revealed that all members exhibited high ...

BACKGROUND Despite the increase in the number of clinical trials in low and middle income countries (LMICs), there has been little serious discussion of whether First in Human (FIH; phase 0 and phase 1) clinical trials should be conducted in LMICs, and if so, under what conditions. Based on our own experience, studies and consultations, this paper aims to stimulate debate on our contention that...

We firstly find the existence of silent event τ in true concurrency (named weakly true concurrency) by defining weakly true concurrent behaviors and weakly true concurrent logics. Based on Paolo Baldan and Silvia Crafa’s comprehensive work on (strongly) true concurrency, we find the correspondence between weakly true concurrent equivalences and weakly true concurrent logics.

The Messenger 170 – December 2017 everyone for all permitted uses. These are governed by CC licenses. Some publishers offer the option for authors to pay an article processing charge (APC) to make individual articles available through open access in otherwise subscription-based journals; this is then called “hybrid OA”. 3. Delayed and temporary OA: Responding to the mandates issued by governmen...

1 Paper prepared for the IMF-World Bank-Brookings conference on Financial Markets and Development. We would like to thank Silvia Iorgova for her efficient and dedicated efforts as a Research Assistant to this project.-2