OBJECTIVE To explore the parent and child acceptable symptom state in juvenile arthritis (JA-PASS and JA-CASS, respectively) and estimate the JA-PASS and JA-CASS cutoff values for outcome measures. METHODS Children with juvenile idiopathic arthritis (JIA) and their parents completed a multi-dimensional questionnaire that included parent-reported and child-reported outcomes and a question abou...

Bestatin, a potent inhibitor of some aminopeptidases, was shown previously to be a powerful inducer of wound-response genes in tomato (Lycopersicon esculentum). Here, we present several lines of evidence showing that bestatin specifically activates jasmonic acid (JA) signaling in plants. First, bestatin specifically activates the expression of JA-inducible genes in tomato and Arabidopsis (Arabi...

Wounding induces a series of coordinated physiological responses essential for protection and healing of the damaged tissue. Wound-induced formation of jasmonic acid (JA) is important in defense responses in leaves, but comparatively little is known about the induction of JA biosynthesis and its role(s) in tuber wound-healing. In this study, the effects of wounding on JA content, expression of ...

We have shown previously that jacaric acid (JA; 8c,10t,12c-18:3), which has a conjugated triene system, has a strong anti-tumor effect. However, the characteristics of absorption and metabolism of JA have yet to be determined in vivo, and the details of absorption and metabolism of JA in the small intestine are particularly unclear. This information is required for effective use of JA in humans...

Jasmonic acid (JA) is a plant hormone that plays important roles in regulating plant defenses against necrotrophic pathogens and herbivorous insects, but the role of JA in mediating the plant responses to root-knot nematodes has been unclear. Here we show that an application of either methyl jasmonate (MeJA) or the JA-mimic coronatine (COR) on Arabidopsis significantly reduced the number of gal...

Inversio-ongelmien teoria on matematiikan ja sen sovellusten kirjossa edelleen varsin nuori tutkimusala. Yksittäisiä ongelmia on toki tutkittu kauan, ja ensimmäinen yhtenäinen osakokonaisuus lienee 1950-luvulla kehitetty Gel’fandin koulukunnan yksiulotteinen käänteinen sirontateoria. Muutaman vuosikymmenen hiljaiselon jälkeen myös moniulotteisissa inversio-ongelmissa saavutettiin läpimurtoja, j...

The endogenous gibberellin (GA) and abscisic acid (ABA) contents as an effect of different application times of jasmonic acid (JA) in chard seedlings exposed to salt stress were investigated. Endogenous ABA content was increased by JA treatment after NaCl treatment, rather than after JA application before NaCl treatment. JA application after NaCl treatment caused higher ABA content than treatme...

Jasmonic acid (JA) and methyl jasm onate (JA-Me, 1) are naturally occurring substances in plants. They are representatives of a group of plant growth regulators [1], The exact quantifica­ tion of JA in plant materials is of great interest for further studies on transport, metabolism and en­ dogenous importance of JA. Using the GC/M SSIM method deuterium-labelled JA should be a good internal sta...

Topological indices are numerical parameters of a molecular graph G which characterize its topology. On the other hands, computing the connectivity indices of molecular graphs is an important branch in chemical graph theory. Therefore, we compute First Zagreb index Zg   <span style="font-family: TimesNewRomanPS-Italic...

The phytohormone jasmonic acid (JA) is known to mediate herbivore resistance, while salicylic acid (SA) and non-expressor of PR-1 (NPR1) mediate pathogen resistance in many plants. Herbivore attack on Nicotiana attenuata elicits increases in JA and JA-mediated defenses, but also increases SA levels and Na-NPR1 transcripts from the plant's single genomic copy. SA treatment of wild-type plants in...