Purpose Juvenile xanthogranuloma (JXG) is a rare histiocytic skin disease primarily of young children, which may also affect ocular structures and in particular the iris. Observations This is a case report of a fifty-year-old patient without skin lesions showing a progressive decrease of visual acuity, iris vascularization and a yellowish iris tumor in the iridocorneal angle of his right eye....

Juvenile Xanthogranuloma (JXG) is a benign proliferative disorder of non-Langerhans histiocytes, occurring in vast majority of cases as multiple, selflimited, cutaneous lesions of children in the first two decades of life [1]. Extracutaneous manifestations of JXG are uncommon, and isolated JXG involving the spinal column is extremely rare [2]. We hereby report the clinicopathological features o...

Juvenile xanthogranuloma is a non-Langerhans cell histiocytosis that typically affects children, but several cases have been reported in adults, some in connection with hematologic malignancies. We present the case of a 61-year-old woman with multiple xanthogranulomas who developed a follicular lymphoma after 4 years of follow-up. After 6 months of treatment with chemotherapy and rituximab, the...

Background Solitary oral mucosal xanthogranuloma, previously termed juvenile is exceedingly rare in adults. Extracutaneous lesions are similarly rarely seen; and the condition generally affects infants children.Methods This case report documents only second occurrence of an adult xanthogranuloma on palatal mucosa. For clinician, a differential diagnosis presented to include several disease cate...