OBJECTIVE The aim of the study was to determine the apoptotic features and proliferation potential of odontogenic keratocysts compared with ameloblastomas and radicular cysts by analysing the role of bax, bcl-2, and Ki-67. MATERIAL AND METHOD The study material consisted of 20 odontogenic keratocysts, 20 radicular cysts, and 20 ameloblastomas. Immunohistochemically, bax, bcl-2 and Ki-67 were ...

Background: TNF-α is a multifunctional proinflammatory cytokine and TGF-β1 is a secretory protein controlling epithelial proliferation and differentiation. Keratocyst presents an aggressive behavior and a growth mechanism different from that of radicular cyst. Aim: In this line, the present study aimed at evaluating TNF-α and TGF-β1 level and its association with histopath...

JADA, Vol. 134, July 2003 877 The canine region is the most common location for the odontogenic keratocyst in the maxilla. D E N T I S T R Y & M E D I C I N E views and intraoral periapical films, in most cases are adequate to determine the location and estimate the size of an OKC. Advanced imaging techniques like computerized tomography and magnetic resonance imaging can be useful in large cas...

Odontogenic keratocyst is a developmental odontogenic cyst that usually diagnosed in routine radiographs the early stages. This fact increases dentist’s responsibility for its diagnosis, and professional should pay attention to all maxillomandibular complex not only teeth. There no standard protocol treatment of keratocyst. However, surgical resection recommended because high recurrence rate, e...

The possibility that the presence of lactoferrin in aspirates of odontogenic cyst fluid might be a useful preoperative diagnostic marker for odontogenic keratocyst was investigated. Using qualitative and quantitative immunodiffusion methods fluid from 29 of 29 dental (radicular) cysts, 12 of 14 dentigerous cysts and 27 of 31 keratocysts were found to contain lactoferrin. Although some of the hi...

A case of central carcinoma of the mandible arising from a recurrent odontogenic keratocyst is reported. A 38-year-old man was admitted to the Tokai University Hospital due to postoperative infection of a recurrent odontogenic keratocyst of the left mandible. He had had a cystectomy for an odontogenic keratocyst 4 years ago. The lesion revealed bony destruction of the mandible with worm-eating ...

background: tnf-α is a multifunctional proinflammatory cytokine and tgf-β1 is a secretory protein controlling epithelial proliferation and differentiation. keratocyst presents an aggressive behavior and a growth mechanism different from that of radicular cyst. aim: in this line, the present study aimed at evaluating tnf-α and tgf-β1 level and its association with histopathological findings in t...

OKC has been of special interest because of aggressive behavior, specific histopathological features, and high recurrence rate.4 The WHO has designated keratocyst OKC as a keratocystic odontogenic tumor because of its neoplastic nature and defined as a benign unior multicystic intraosseous tumor of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epitheliu...

We present a case of an odontogenic keratocyst discovered as incidental finding in the anterior mandible young female patient. This is unusual presentation, and very few cases affecting are reported literature.