Amiodarone (AMD)-induced pulmonary toxicity (AIPT) is the most life-threatening side-effect of AMD treatment. N-Monodesethylamiodarone (DEA), an active metabolite of AMD, also exhibits cytotoxicity and tends to accumulate in the lung more intensively than AMD. In this study, we characterized the mechanism of DEA accumulation using A549 cells as a model of the alveolar epithelium. Typical ATP-de...

In this paper, we discuss the relationship between multi-attribute utility theory and DEA models without explicit inputs (DEA-WEI), including dual models and some theoretical analysis of DEA-WEI models. We then propose generic DEA-WEI models with quadratic utility terms. Finally, we provide illustrative examples to show that DEA-WEI with suitable quadratic utility terms are able to reflect some...

Diethanolamine (DEA) is a common ingredient of personal care products. Dermal administration of DEA diminishes hepatic stores of the essential nutrient choline and alters brain development. We previously reported that 80 mg/kg/day of DEA during pregnancy in mice reduced neurogenesis and increased apoptosis in the fetal hippocampus. This study was designed to establish the dose-response relation...

This paper adopts a two-stage data envelopment analysis to explore the impacts of financial development and bank operating scale on bank efficiencies. The sample comprises unbalanced panel data of 32 Taiwanese listed domestic commercial banks over the period 1998 to 2013. Empirical results show that pure technical efficiency is positively related to financial development, whereas the effect of ...

The after–sales activities are nowadays acknowledged as a relevant source of revenue, profit and competitive advantage in most manufacturing industries. Top and middle management, therefore, should focus on the definition of a structured business performance measurement system for the after-sales business. The paper aims at filling this gap, and presents an integrated methodology for the after-...

Nowadays, technological progress is one of the most important components of economic growth and the efficiency of R&D activities is particularly essential for countries. This study is an attempt to analyze the R&D efficiencies of EU countries. The indicators related to R&D efficiencies should be determined in advance in order to use DEA. For this reason a list of input and output indicators are...

The purpose of this paper is to investigate the levels of technical efficiency in agricultural sector of MENA countries by using Data Envelopment Analysis (DEA) and Stochastic Frontier Analysis (SFA) approaches in 2007-2008. The results show that the total average of technical efficiency is as follows: DEABCC(0.770)>DEACCR(0.744)>SFA(0.479), and among all MENA countries, the best performanc...