conclusions the present study confirms the notion of selecting endophytic fungi of medicinal plant justicia for the bioassay-guided isolation of its bioactive compounds, and demonstrates that endophytic fungus chaetomium sp. nf15 could be a potential source of bioactive metabolites materials and methods endophytic fungi associated with the j. adhatoda l. plant were isolated from healthy plant p...

Biological control consists of using one organism to attack another that may cause economic damage to crops. Integrated Pest Management (IPM) is a very common strategy. The white mold produced by Sclerotinia sclerotiorum (Lib.) causes considerable damage to bean crops. This fungus is a soil inhabitant, the symptoms of which are characterized by water-soaked lesions covered by a white cottony fu...

Endophytic fungi were used not only for their producing bioactive products but also for their ability to transform natural compounds. An endophytic fungus, isolated from medicinal plant Huperzia serrata, was identified as Umbelopsis isabellina based on the internal transcribed spacer of ribosomal DNA (rDNA-ITS) region. It was used to transform ursolic acid (1), a pentacyclic triterpene. Incubat...

Background information: The phytochemicals of endophytes have generated substantial interest in drug discovery programs because they offer the possibility discovering new biologically active molecules. Objective: objective this study was to quantify and analyze phytochemical profile fungus endophytic extracts isolated from Azadirachta indica leaves, which been used ethnobotanically for treating...

Chloropupukeanolides A (1) and B (2), unprecedented spiroketal peroxides, and chloropupukeanone A (3), three highly functionalized metabolites featuring a chlorinated pupukeanane core, were isolated from an endophytic fungus Pestalotiopsis fici, with 1 showing significant anti-HIV-1 and cytotoxic effects.

Penicillium janczewskii K. M. Zalessky was isolated as an endophytic fungus from the phloem of the Chilean gymnosperm Prumnopitys andina. When grown in liquid yeast extract-malt extract-glucose broth, the fungus produced two main secondary metabolites. The compounds were for the first time isolated from this species and identified by spectroscopic methods as pseurotin A and cycloaspeptide A. Th...

The entomopathogenic fungus Beauveria bassiana was re-isolated from surface sterilized pieces of the cocoa pod outer section and peduncle, two and three months after flowers of greenhouse cocoa plants were hand-pollinated and sprayed with a 1x107 mL-1 suspension of B. bassiana conidia. The colonization frequency of B. bassiana on cocoa pods was 0.8% and 1.3% two and three months post-spraying o...

Epichloe typhina is an endophytic fungus, while Cladosporium phlei is a pathogenic fungus of the timothy plant (Phleum pretense L.). We found two activities in the culture filtrate of E. typhina: one stimulated the pathogenic fungus, C. phlei, to produce phleichrome and the other inhibited its growth. The active ingredients that stimulated the production of phleichrome and inhibited the growth ...

The small-molecule biosynthetic potential of most filamentous fungi has remained largely unexplored and represents an attractive source for the discovery of new compounds. Genome sequencing of Calcarisporium arbuscula, a mushroom-endophytic fungus, revealed 68 core genes that are involved in natural product biosynthesis. This is in sharp contrast to the predominant production of the ATPase inhi...