the purpose of this study was to investigate the effects of short-term creatine monohydrate (cr) and folic acid (fa) supplementation on homocysteine (hcy) levels in young active males. eighteen young male soccer players (21.11±2.02 years, vo2max 56.51±2.31, hcy 13.45±0.59) volunteered to participate in this study. they were randomly divided into creatine monohydrate (n=6), folic acid (n=6) and ...

Abstract
 Objective: This study aimed to investigate the antioxidant effects of folic acid and its on contraction relaxation responses in rat aorta hyperhomocysteinemic rats.
 Methods: Thirty-four male Wistar Albino rats were allocated into four groups. Rats hyperhomocysteinemia group (Group 1, n=9) received 1g/kg/day methionine via orogastric gavage for 30 days then injected with int...

hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. the present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on ph-sensitive polymers such as poly (acrylic acid). poly (acrylic acid), p(aa), hydrogel has been synthesized by radical po...

background: the human immunodeficiency virus (hiv) is one of the most life- threatening human infections. the advent of highly active antiretroviral therapy (haart) has dramatically changed the course of hiv infection and patients' quality of life. in addition to the benefits, haart can have numerous side effects and toxicities. therefore, we aimed to assess the impact of short-term vitamins tr...

background: leber hereditary optic neuropathy (lhon) is an inherited form of bilateral optic atrophy leading to the loss of central vision.  the primary cause of vision loss is mutation in the mitochondrial dna (mtdna), however, unknown secon­dary genetic and/or epigenetic risk factors are suggested to influence its neuropathology.  in this study folate gene polymor­phisms were examined as a po...

Folic acid plays a basic role in fetal growth, development and prevents fetalmalformations. Pregnant woman's perception regarding folic supplementation is critical

background: spina bifida and anencephaly are among serious and fatal anomalies in infants that may lead to a 50-70% of reduction in incidence when folic acid is consumed before conception. methods: in a cross sectional study, 2997 pregnant women were evaluated to determine the level of their knowledge and practice about using folic acid in fars province, southern iran. results: eighty percent o...

In this work, the structural and electronic properties of folic acid molecule on functionalized (7,0)zigzag single-walled carbon nanotube was studied in gas phase on the basis of density functionaltheory (DFT). Furthermore, covalent interaction of folic acid with single-walled carbon nanotube wasinvestigated and its quantum molecular descriptors and binding energies were calculated. The DFTB3LY...