Amelogenesis Imperfecta (AI) can be caused by the deficiencies of enamel matrix proteins, molecules responsible for the transportation and secretion of enamel matrix components, and proteases processing enamel matrix proteins. In the present study, we discovered the double deletion of bone morphogenetic protein 2 (Bmp2) and bone morphogenetic protein 4 (Bmp4) in the dental epithelium by K14-cre...

Amelogenin, enamelin, sheathlin (ameloblastin/ amelin), enamelysin (MMP-20), and KLK4 (EMSP-1) are the major structural proteins and proteinases in developing tooth enamel. Recently, odontoblasts were reported to express amelogenin, the most abundant enamel protein. In this study, we hypothesized that odontoblasts express all enamel proteins and proteases, and we measured their relative mRNA le...

There are many available technologies that can assist future teachers to deliver instruction. The purpose of this paper is to provide a brief review of literature identifying available technology tools in mathematics education and which technologies are selected by PSTs to design mathematics lesson activities. The most commonly used and available technology tools in mathematics education and th...

We examine the problem of learning a model of a deterministic dynamical systems from experience. A handful of representation schemes have been proposed for capturing such systems, including POMDPs, PSRs, EPSRs, Diversity, and PSTs. We argue that no single representation should be expected to be ideal in all situations and describe an approach for learning the most succinct representation of an ...

Disruption of pstS encoding the P(i)-binding protein in Escherichia coli generally leads to the constitutive expression of the pho regulon. We demonstrate that P(i)-controlled expression is restored when the activity of the P(i) transporter PitA or PitB is increased. Apparently, PstS is not an essential component of the signal transduction pathway.

BACKGROUND All human kallikrein (KLK) genes have at least one splice variant, some of which possess clinical utility in cancer diagnostics/prognostics. Given that introns <100 bp in length are retained in 95% of human genes and that splice variants of KLK3 and KLK4 retain intron III, we hypothesized that other proteins in this family, with a small intron III, may also retain it. METHODS Varia...

background: amelogenesis imperfecta (ai) is an inherited tooth disorder. despite the fact that up to now, several gene muta­tions in mmp20, enam, amelx and klk4 genes have been reported to be associated with ai, many other genes sug­gested to be involved. the main objective of this study was to find the mutations in three major candidate genes including mmp20, enam and klk4 responsible for ai f...