Abstract. The same unetched and chemically etched apatite crystals from five rock samples were dated by the U–Pb method via laser ablation inductively coupled plasma mass spectrometry (LA–ICP-MS). objective of this study is to test whether chemical etching required for fission track analysis impacts precision accuracy geochronology. results experiment suggest that has insignificant effects on a...

Phosphorus, sulfur, silicon and metal concentrations (Al, Cu and Zn) were determined in human brain proteins by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) after separation of protein mixtures by two dimensional (2-D) gel electrophoresis. The analysis of phosphorus, silicon and metals in single protein spots in the gel was performed with an optimized microanalytical ...

Due to developments in reaction cell technologies, it is now possible collect large 87 Rb/ 86 Sr and Sr/ data sets using LA‐ICP‐MS/MS. Until now, LA‐ICP‐MS/MS Rb‐Sr ages were constrained conventional isochrons on a contiguous set of data. In this contribution, we present straightforward procedure how measure, calculate validate from individual laser spots even detrital grains devoid context. Th...

Like in the previously published LA-ICP-MS method, sample itself acts as perfectly matrix matched reference material, but combination with isotope dilution improves uncertainty and accuracy of novel LA-ID-ICP-MS method.

In order to clarify the histological localization of cadmium (Cd) in the placenta, we analyzed paraffin sections of placentas from rats with a single Cd exposure on gestation day 18 by the LA-ICP-MS imaging method compared with the histopathological changes. The placentas were sampled at 1 hour, 2 hours, 3 hours, 6 hours, and 24 hours after treatment. Histopathologically, the trophoblasts in th...

Cellular therapy is emerging as a promising alternative to conventional immunosuppression in the fields of haematopoietic stem cell (HSC) transplantation, autoimmune disease and solid organ transplantation. Determining the persistence of cell-based therapies in vivo is crucial to understanding their regulatory function and requires the combination of an extremely sensitive detection technique a...

Abstract. Many new geochronological applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) have been proposed in recent years. One the problems associated with this rapid growth is lack chemically and isotopically homogeneous matrix-matched primary standards to control elemental fractionation during LA-ICP-MS analysis. In U–Pb problem often addressed by utilisin...

The two obsidian sources from the island of Melos (Greece), Agia Nychia and Demenegakion, are chemically characterized by three complementary analytical techniques. Ion beam analysis (IBA) comprising particle induced X-ray emission and particle induced gamma-ray emission, neutron activation analysis (NAA) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is applied to ...

Cellular therapy is emerging as a promising alternative to conventional immunosuppression in the fields of haematopoietic stem cell (HSC) transplantation, autoimmune disease and solid organ transplantation. Determining the persistence of cell-based therapies in vivo is crucial to understanding their regulatory function and requires the combination of an extremely sensitive detection technique a...

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