نتایج جستجو برای: lamotrigine monotherapy
تعداد نتایج: 16820 فیلتر نتایج به سال:
Although a relatively common behavior, treatment data for pathological skin picking (PSP) are limited. The current study sought to examine the efficacy and tolerability of lamotrigine in adults with PSP and to examine neurocognitive predictors of treatment response. Thirty-two subjects (29 female subjects [90.6%]; mean age, 32.8 +/- 13.3 years) with PSP were treated in a 12-week randomized, dou...
BACKGROUND Bipolar disorder is a highly recurrent disease and has great impact on the function of patients. Depressive symptoms consist of more than 50% of life time during the illness and may lead to self harm or suicidal behaviors. Little is known about the antidepressant effects of olanzapine, an atypical antipsychotic, as monotherapy despite its indication for preventing manic episodes. In ...
Toxic epidermal necrolysis (TEN) is a rare, but very severe cutaneous disorder characterized by necrosis of keratinocytes leading to a loosening of the epidermis’**. As a consequence, lifethreatening dehydration and severe infections may occur. TEN can occur as a result of an adverse reaction to drugs (i.e. Lye11 syndrome) or may be the result of staphylococcal toxins (i.e. staphylococcal scald...
The Canadian Network for Mood and Anxiety Treatments (CANMAT) published guidelines for the management of bipolar disorder in 2005, with a 2007 update. This second update, in conjunction with the International Society for Bipolar Disorders (ISBD), reviews new evidence and is designed to be used in conjunction with the previous publications. The recommendations for the management of acute mania r...
OBJECTIVE Some patients with symptoms of binge eating and purging are successfully treated with specific serotonin reuptake inhibitors (SSRIs), but others experience only partial or no benefit. Significant affect dysregulation and poor impulse control may be characteristics that limit responsiveness. METHOD We report on the treatment of five patients with bulimia nervosa (BN), anorexia nervos...
We prospectively surveyed 23 pregnant women with epilepsy on lamotrigine monotherapy and reported outcome of their pregnancies, including one fetal intrauterine death, one spontaneous abortion and two preterm deliveries. There were no congenital malformations in their offspring. Women with pregnancy planning and folic acid intake delivered babies with higher values of birth weight and birth len...
We have developed a simple and rapid high performance liquid chromatographic technique to determine lamotrigine concentrations in epileptic patients and validated it using external quality control material. The method has been used to monitor the lamotrigine concentration in 70 specimens from 61 patients. Only 50% of the specimens had concentrations within the proposed target range of 1 mg/L to...
An Online First version of this article was made available online at http://link.springer.com/journal/40263/ onlineFirst/page/1 on 22 April 2017. An error was subsequently identified in the article, and the following correction should be noted: Page 1, abstract, column 2, lines 2–6: The following sentence, which previously read: ‘‘... in utero exposure to lamotrigine monotherapy was found to be...
OBJECTIVE To assess the course of sexual function in epilepsy patients treated with lamotrigine. MATERIAL AND METHODS This open study included 141 patients treated with lamotrigine for a period of 8 months: 79 patients initiated treatment with lamotrigine monotherapy, and 62 were switched to lamotrigine because of lack of efficacy or adverse events to a previous antiepileptic drug (AED). Pati...
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