Although alternative splicing has been shown to give rise to isoforms of a number of transcription factors, such isoforms have not previously been detected for the POU homeodomain protein Pit-1. Screening of a rat pituitary GH3 cell cDNA expression library yielded a clone, termed pCMVPit-1a, encoding a 35.8 kD protein (Pit-1a) containing a 26 amino acid insert in the Pit-1 trans-activation doma...

Recent studies have suggested that species-specific pit properties such as pit membrane thickness, pit membrane porosity, torus-to-aperture diameter ratio and pit chamber depth influence xylem vulnerability to cavitation. Despite the indisputable importance of using mean pit characteristics, considerable variability in pit structure within a single species or even within a single pit field shou...

One of the main concerns of the mining industry is to determine ultimate pit limits. Final pit is a collection of blocks, which can be removed with maximum profit while following restrictions on the slope of the mine’s walls. The size, location and final shape of an open-pit are very important in designing the location of waste dumps, stockpiles, processing plants, access roads and other surfac...

The purpose of this study was to compare the assessment of caries patterns by clinical definition and by cluster analysis. One of five etiology-oriented caries patterns was assigned to Head Start children in primary dentition. Cluster analysis grouped children based on carious tooth surfaces for each child. One hundred twenty-seven of the 155 children with at least one carious lesion fell into ...

Pavlovian conditioned stimuli can influence instrumental responding, an effect called Pavlovian-instrumental transfer (PIT). During the last decade, PIT has been subdivided into two types: specific PIT and general PIT, each having its own neural substrates. Specific PIT happens when a conditioned stimulus (CS) associated with a reward enhances an instrumental response directed to the same rewar...

Sungun Copper Mine is located in an area with a high level of seismic hazard. Most recently, the Ahar-Varzeqan earthquake with a magnitude of 6.2 on Richter scale occurred on August 11, 2012; at a distance about 40 kilometers away from the mine. Nevertheless, the seismic stability of the final pit wall has not been comprehensively reviewed. In this research, the southwestern wall of the final p...

The mammalian pit-1 gene encodes a 33 kd transcription factor (1,2) expressed in a subset of endocrine cells of the anterior pituitary (3). Pit-1 is structurally related to the POU family of transcriptional regulators (4), containing a characteristic POU domain divided into two regions, the POU-specific and homeo subdomains. Located in the C-terminal half of the protein, the POU domain is criti...

One of the most effective parameters in economics of open-pit mines is the pit slope angle, so that the slope angle more than the optimum value increases the probability of a large failure in the pit wall and the slope angle less than the optimum value leads to increasing stripping ratio and reducing net present value of mine. Therefore, in this paper, considering the limit equilibrium methods ...

Deep foundation pit construction adjacent to a subway station in soft soil area was numerically simulated with Midas GTS NX calculation software. The influence of the deep on deformation and stress structure studied, retaining analyzed. results show that during excavation process, slab rose as whole greatly affected by common ground connecting wall, most unfavorable position changing changed. p...

The air-seeding hypothesis predicts that xylem embolism resistance is linked directly to bordered pit functioning. We tested this prediction in trunks, roots, and branches at different vertical and radial locations in young and old trees of Pseudotsuga menziesii. Dimensions of bordered pits were measured from light and scanning electron micrographs, and physiological data were from published va...