Laryngeal cancer is the most frequent neoplasm in the head and neck region, with the vast majority of tumors originating from squamous cells. The survival rate of patients with laryngeal cancer has not improved substantially over the past 25 years. To acquire further knowledge regarding the molecules responsible for laryngeal cancer oncogenesis and, in turn, to improve target therapy iTRAQ and ...

on laryngeal diseases, an approach towards approximate accuracy. Eppinger (Pathologische Anatomie des Larynx und der Trachea, p. 205) quite correctly mentions the three examples which had been observed up to the year 1880,?to wit, those of Wagner, Tobold, and Brans. With regard to Wagner's case, he gives the reference as Archiv fur Prakt. Heilkunde, 1872, p. 108, and states, in a somewhat aggri...

Chondrosarcoma (CS) of the larynx was first described in 1935. Cartilaginous tumours of the larynx are largely rare and there is little literature concerning them. Laryngeal CS manifest with a different pathological behaviour to other malignancies of the larynx and as such the treatment of these neoplasias are different. The purpose of this review is to present a detailed report of the laryngea...

We report a case of pulmonary sarcoidosis, which initially presented as a left apical infiltrate. The later course mimicked a pulmonary neoplasm, with left upper lobe atelectasis secondary to bronchial stenosis, resulting from both endobronchial sarcoidosis and extrinsic compression by enlarged lymph nodes. Extrinsic pressure from sarcoid nodes on the left main pulmonary artery and recurrent la...

In this paper an approach is presented which is aimed to enhance disordered male voices. This approach aims at highpitched voices with a severe degree of hoarseness. The goal of the study is to determine whether pitch modification combined with periodicity enhancement can improve the perceived quality of a disordered speech utterance. Signal manipulation is done pitch-synchronously, so, firstly...

A tracheoesophageal fistula (TEF), albeit rare, can be a life-threatening condition that requires prompt identification and treatment. Pulmonary contamination and restriction of proper nutrition are common, unfortunate consequences of untreated TEFs and are often the causes of mortality in this population. In our patient, a history of laryngeal malignancy along with symptoms of chest pain and c...

background laryngeal cancer though accounts for only 1.5% of all malignant neoplasm. scientific evidence has shown that cancers of the oral cavity, larynx, lung and esophagus are associated with cigar smoking. the present study is to examine by case-control method the impact of smoking on laryngeal cancer. material and methods one hundred and six hospitalized cases of otolaryngology department ...

Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs mainly in the soft tissues of head and neck region, with the paranasal sinuses, nasal cavity and nasopharynx being the most common sites. Solitary EMP of the larynx is very rare but increasingly reported recently. Common sites of involvement in larynx in the order of frequency are the epiglottis, ventricles, vocal fold...

Schwannomas are benign tumours, rare among tumours of the larynx. They normally present as supraglottic masses (because they may arise from the internal branch of the superior laryngeal nerve), most commonly involving aryepiglottic folds or false vocal folds. Most patients present with a globus sensation, dysphagia or hoarseness. Conservative surgery is the treatment of choice. We report a case...