Goiter is an enlargement of the thyroid gland which can be associated with a number of complications both for mother and fetus. A 34-year-old pregnant woman with normal function was referred to our Department Obstetrics and Gynecology at Microcitemico Pediatric Hospital, Cagliari, suspected fetal goiter 32 gestational weeks. The case monitored regularly by ultrasound and treated successfu...

The Incidence of laryngotracheal stenosis is increasing nowadays due to increasing incidence of prolonged endotracheal intubations with increasing incidence of polytrauma, neurovascular accidents, and complex surgical procedures with subsequent intensive care units admission, intubation with or without ventilation. Improvement in the protocols of intensive care increased the numbers of patients...

OBJECTIVES/HYPOTHESIS Vocal cord scar formation and laryngotracheal stenosis (LTS) are challenging problems for otolaryngologists. Sendai virus (SeV) vectors have been shown to transduce airway epithelium efficiently, and are thus ideal for modulating airway wound-healing therapy. To assess the potential utility of SeV gene therapy for laryngotracheal diseases, we established a novel LTS model ...

BACKGROUND Treatment for adult subglottic stenosis is technically demanding and no therapeutic algorithm exists. We performed the present meta-analysis of treatment for this condition in an attempt to compare efficacy on the basis of type of procedure. METHODS We identified 24 eligible retrospective studies reporting the therapeutic results for inclusion criteria. Meta-analysis was performed ...

OBJECTIVES/HYPOTHESIS To establish an animal model for post-intubation laryngotracheal injuries resulting in significant laryngotracheal insult without compromising the survival of the animal for a minimum period of 12 weeks post-extubation. To study the extent of injury based on morphometric and histopathological change seen at 12 weeks post-extubation. STUDY DESIGN Randomized block, single-...

Objective The treatment of laryngotracheal stenosis is a major therapeutic challenge. Various treatments include observation, medical management, and surgical management. The most effective surgical management is resection and reconstruction. To the authors' knowledge, no reports have described the use of xenogenic acellular dermal matrix (ADM) for laryngotracheal stenosis. Methods A 27-year-ol...

BACKGROUND Adult laryngotracheal reconstruction for airway stenosis and after oncologic ablation can be extremely challenging. METHODS Patients with the above conditions not amenable to or refractory to conventional treatments were offered specialized reconstruction by wrapping a contoured costal cartilage graft with a vascularized microvascular carrier. All constructs were lined with buccal ...

BACKGROUND Superimposed high-frequency jet ventilation (SHFJV), which does not require any tracheal tubes or catheters, was developed specifically for use in laryngotracheal surgery. SHFJV uses two jet streams with different frequencies simultaneously and is applied in the supraglottic space using a jet laryngoscope and jet ventilator. METHODS Between 1990 and 2004, SHFJV was studied in 1515 ...