Androgen deficiency is important in the pathophysiology of atrial fibrillation. Androgen regulates cardiac electrophysiology and calcium (Ca(2+)) homeostasis. The purpose of this study is to evaluate whether androgen receptor knockout (ARKO) can modulate atrial electrophysiology and arrhythmogenesis with modulation of Ca(2+) homeostasis proteins. We used conventional microelectrodes to study th...

a Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas, Spain b Servicio de Radiodiagnóstico, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas, Spain c Servicio de Microbiología, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria,...

For uniform oriented matroids M with n elements, there is in the realizable case a sharp lower bound Lr (n) for the number mut(M) of mutations ofM : Lr (n) = n ≤ mut(M), see Shannon [17]. Finding a sharp lower bound L(n) ≤ mut(M) in the non-realizable case is an open problem for rank d ≥ 4. Las Vergnas [9] conjectured that 1 ≤ L(n). We study in this article the rank 4 case. RichterGebert [11] s...

Tourists planning to visit the United States have many exciting destinations to choose from. The number of people visiting the USA is on the rise, and their spending is growing even faster thus increasing the value of tourism to the economy. International arrivals and domestic travelers have increased over the last decade. However, for as many historical landmarks, amazing nightlife scenes, and...

1967 Berkeley 1968 Berkeley 1969 Asilomar 1970 Tucson 1971 Asilomar 1972 Claremont 72:01–72:05 1973 Los Angeles 73:01–73:16 1974 Los Angeles 74:01–74:08 1975 Asilomar 75:01–75:23 1976 San Diego 1–65 i.e., 76:01–76:65 1977 Los Angeles 101–148 i.e., 77:01–77:48 1978 Santa Barbara 151–187 i.e., 78:01–78:37 1979 Asilomar 201–231 i.e., 79:01–79:31 1980 Tucson 251–268 i.e., 80:01–80:18 1981 Santa Bar...

The local anaesthetics (LAs) are widely used for peripheral nerve blocks, epidural anaesthesia, spinal anaesthesia and pain management. However, exposure to LAs for long duration or at high dosage can provoke potential neuronal damages. Autophagy is an intracellular bulk degradation process for proteins and organelles. However, both the effects of LAs on autophagy in neuronal cells and the effe...

Using hashing techniques, this paper develops a family of space-efficient Las Vegas randomized algorithms for k-SUM problems. This family includes an algorithm that can solve 3-SUM in O(n) time and O( √ n) space. It also establishes a new time-space upper bound for SUBSETSUM, which can be solved by a Las Vegas algorithm in O(2 √ 8 9 ) time and O(2) space, for any β ∈ [0, 9 32 ].

Instituto Español de Oceanografı́a, Centro Oceanográfico de Canarias (IEO-COC). Santa Cruz de Tenerife, Spain, Universidad de Las Palmas de Gran Canaria, Instituto de Oceanografı́a y Cambio Global (IOCAG). Las Palmas, Spain, Universidad de Las Palmas de Gran Canaria, Banco Español de Algas (BEA). Las Palmas, Spain, Instituto Geográfico Nacional, Centro Geofı́sico de Canarias. Santa Cruz de Tenerif...

Of our 153 metropolitan areas, the median number of permits per thousand population per year over the study period (1980 to 1993) was 5.8. However there was a large amount of variation in this data. Las Vegas had slightly over 22 permits per thousand, as did Ft. Myers, Florida. West Palm Beach had about 21 permits per thousand, Orlando 18.5 permits per thousand, and Melbourne 16.4 permits per t...