Fluorescence imaging is a tool of increasing importance in aerodynamics, fluid flow visualization, and nondestructive evaluation in a variety of industrial circumstances. It is a means for producing two-dimensional images of real surfaces or fluid case-sectional areas that correspond to data on properties such as temperature or pressure across the surfaces. This article discusses three major fl...

The analysis of speckle contrast in a time-integrated speckle pattern enables visualization of superficial blood flow in exposed vasculature, a method we call laser speckle imaging (LSI). With current methods, LSI does not enable visualization of subsurface or small vasculature, because of optical scattering by stationary structures. In this work we propose a new technique called photothermal L...

Aetna considers in-vivo analysis of colorectal polyps (e.g., chromoendoscopy, confocal laser [fluorescent] endomicroscopy [including Cellvizio probe-based confocal laser endomicroscopy], endocytoscopy, EVIS EXERA 160A System, fiberoptic analysis, multi-band imaging, narrow-band imaging optical chromocolonoscopy, Optical Biopsy System, Pentax Confocal Laser System, and WavSTATTM Optical Biopsy S...

Ultrahigh resolution optical coherence tomography (OCT) is performed with a broadband, Kerr-lens mode-locked, diode-pumped Cr(3+):LiCAF laser. The laser source has a bandwidth of 89 nm with an output power of 37 mW. OCT imaging is demonstrated with 4.5 microm axial resolution in air or 3.4 microm in tissue. In vivo imaging of the human retina is demonstrated. Ultrahigh resolution OCT images fro...

We demonstrate an imaging technique implementing vertical cavity lasers with extremely low transient times for a greatly simplified realization of a multiexposure laser speckle contrast imaging system. Data from multiexposure laser speckle imaging was observed to more closely agree with absolute velocity measurements using time of flight technique, when compared to long-exposure laser speckle i...

ABSTRACT Background: Osteoid osteoma is a benign bony neoplasm and its classic treatment is surgery. In the r ecent decades percutaneous laser therapy was suggested to be replaced by surgery. In this study we have reviewed the results of the first applications of interstitial laser photocoagulation (ILP) for treatment of osteoid osteoma in Iranian patients. Materials and Methods: In this case s...

This work presents, to our knowledge, the first demonstration of the Laser Speckle Contrast Imaging (LSCI) technique with extended depth of field (DOF). We employ wavefront coding on the detected beam to gain quantitative information on flow speeds through a DOF extended two-fold compared to the traditional system. We characterize the system in-vitro using controlled microfluidic experiments, a...

The development of the scanning laser ophthalmoscope (SLO), first conceived by Webb et al in 1980 heralded the first widespread application of lasers for retinal imaging. A highly collimated beam from a laser is swept over the retina delivering all its energy to a very small spot for a very short time, typically of the order of some tens of nanoseconds. Light reflected from the spot is detected...

Laser Speckle Contrast Imaging (LSCI) is a minimally invasive full field optical technique used to generate blood flow maps with high spatial and temporal resolution. The lack of quantitative accuracy and the inability to predict flows in the presence of static scatterers such as an intact or thinned skull have been the primary limitation of LSCI. We present a new Multi-Exposure Speckle Imaging...