Short chain (SCAD), medium chain (MCAD), and long chain acyl-CoA dehydrogenases (LCAD) catalyze the first step of fatty acid oxidation, while isovaleryl-CoA dehydrogenase (IVD) is involved in leucine oxidation. They are homologous flavoproteins belonging to the acyl-CoA dehydrogenase (ACD) family. Electron transfer flavoprotein (ETF) serves as an obligatory electron acceptor for these reactions...

Type 1 diabetes mellitus is a devastating disorder affecting both glucose and lipid metabolism. Using the nonobese diabetic (NOD) mouse model, we found that diabetic mice had a liver-specific increase in steady state mRNA levels for enzymes involved in oxidation of fatty acids. Increased mRNA abundance was observed in very long-chain acyl-CoA dehydrogenase, long-chain acyl-CoA dehydrogenase (LC...

the composition of essential oil of leaves of the male and female shrubs of juniperus chinensis l. (growing in isfahan) was analyzed by gas choromatography(gc) and gc-mass spectrometery (ms). the main constituents of leaf oil of the male shrub were: bornyl acetate (26.1%), sabinene (18.3%), trans-sabinyl acetate (11.1%), myrcene (9.2%), limonene (6.1%), elemol (5.5%), α-cadinol (2.3%), δ-cadine...

The sirtuins are a family of nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylases that regulate cell survival, metabolism, and longevity. Humans have seven sirtuins (SIRT1-SIRT7) with distinct subcellular locations and functions. SIRT3 is localized to the mitochondrial matrix and its expression is selectively activated during fasting and calorie restriction. Activated SIRT3...

conclusions the results of the present study indicate the protective effects of melissa officinalis on some sperm parameters and spermatogenesis quality in rats exposed to lead. background some medicinal plants with their antioxidant properties have protective effects on sperm parameters and neutralize the harmful effects of lead exposure. objectives the present study aimed to determine the eff...