We studied the effect of administering Cassia auriculata leaf extract to rats with experimentally induced liver damage. Hepatotoxicity was induced by administering 9.875 g/kg bodyweight ethanol for 30 days by intragastric intubation. C. auriculata leaf extract was administered at a dose of 250 mg/kg bodyweight daily in one group and 500 mg/kg bodyweight daily in another group of alcohol-treated...

The methanol leaf extracts of Acacia nilotica, Sida cordifolia, Tinospora cordifolia, Withania somnifer and Ziziphus mauritiana showed significant antibacterial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Staphylococcus aureus and Xanthomonas axonopodis pv. malvacearum and antifungal activity against Aspergillus flavus, Dreschlera turcica and Fusarium verticil...

An attempt was made to evaluate anti-anaemic properties of probiotic Moringa oleifera leaf extract using animal model. Twenty four male rats were randomly assigned to four groups and all the animals were given Phenylhydrazine orally to induce anaemia. Enterococcus durans was selected as probiotic supplement. Group 1 was provided with 300mg/kg of M.oleifera leaf extract. Group 2 was supplemented...

Mulberry leaves are rich in 1-deoxynojirimycin (DNJ), an inhibitor of α-glucosidase. We previously showed that DNJ-rich mulberry leaf extract suppressed elevation of postprandial blood glucose in humans. The objective of this study was to evaluate the effects of DNJ-rich mulberry leaf extract on plasma lipid profiles in humans. An open-label, single-group study was conducted in 10 subjects with...

Nephrotoxicity is a major limiting factor in cisplatin treatment. In the present study hydro-ethanolic leaf extract of Emblica officinalis was investigated for its protective role in cisplatin induced nephrotoxicity. The experiment was designed for 14 days and male Wistar rats were divided into 9 groups (n = 5). Group 1 served as control (with no treatment), group 2 served as a vehicle control ...

The methanol leaf extracts of Acacia nilotica, Sida cordifolia, Tinospora cordifolia, Withania somnifer and Ziziphus mauritiana are ethnomedicinally important showed significant antibacterial and activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Staphylococcus aureus and Xanthomonas axonopodis pv. malvacearum and antifungal activity against Aspergillus flavus, Dresc...

This present study investigated the potential of Morinda citrifolia leaf aqueous extract to induce osteogenic differentiation and matrix mineralization of human periodontal ligament (hPDL) cells. Human periodontal ligament cells were cultured in complete medium, ascorbic acid with β-glycerophosphate, or Morinda citrifolia leaf aqueous extract. Morinda citrifolia leaf aqueous extract significant...

As a measure of testing the medicinal properties of Jatropha curcas, methanol extract obtained from both in vivo leaf and leaf derived callus were subjected to antimicrobial activity against six microorganisms, of the six different concentrations tested, the in vitro leaf callus extracts of at high concentrations (1.0 and 1.2%) inhibited the growth of Staphylococcus aureus and Pseudomonas sp. a...

Quorum sensing (QS) plays an important role in virulence of Pseudomonas aeruginosa, blocking of QS ability are viewed as viable antimicrobial chemotherapy and which may prove to be a safe anti-virulent drug. Bioactive components from Piper betle have been reported to possess antimicrobial ability. This study envisages on the anti-QS properties of ethanolic extract of P. betle leaf (PbLE) using ...

Objective: The aim of this study was to develop and validate an image analysis method for quantitative analysis of barakol content in Senna siamea leaf extract. Methods: TLC-densitometric and TLC-image analysis methods were developed, validated, and used for quantitative analysis of Senna siamea leaf extract. The results obtained by these two different quantification methods were compared by pa...