INTRODUCTION Orthodeoxia is a rare clinical syndrome characterised by dyspnoea and arterial deoxygenation that accompanies a change from a supine to erect position. CLINICAL PICTURE We describe an unusual case of "paradoxical orthodeoxia" in a 70-year-old man with a thoracic aortic aneurysm: arterial desaturation when supine that improved when erect. TREATMENT AND OUTCOME Non-invasive imagi...

BACKGROUND It remains a great challenge to measure systemic blood flow in critically ill newborns. In a former study we validated the modified carbon dioxide Fick (mCO(2)F) method for measurement of cardiac output in a newborn lamb model. In this new study we studied the influence of a left-to-right shunt on the accuracy of the mCO(2)F method. OBJECTIVE To analyze the influence of a left-to-r...

BACKGROUND To determine impact of intraluminal-left anterior descending shunt to prevent myocardial damage in minimally invasive coronary artery bypass. METHODS 38 patients were randomly assigned to external tournique occlusion (n = 19) or intraluminal-left anterior descending shunt group (n= 19). Blood samples for cardiac troponin T were collected at 30 minutes prior to, 6 and 24 hours after...

We studied the effect on the circulation of the catecholamines isoproterenol, dopamine, and dobutamine in chronically instrumented lambs with aortopulmonary left-to-right shunts (ages 11 to 87 days) and without shunts (ages 8 to 97 days). Infusion of 0.1 microgram/kg/min isoproterenol or 10 micrograms/kg/min dobutamine markedly increased heart rate and systemic and pulmonary blood flows, while ...

An in situ perfused crocodile (Crocodylus porosus) heart preparation was developed to investigate the effects of input and output pressure on cardiac dynamics and to determine the conditions that lead to a right-to-left cardiac shunt. The pericardium was kept intact, both the left and right atria were perfused and all three outflow tracts (right aortic, left aortic and pulmonary) were cannulate...

Abnormal Left Coronary Artery from Pulmonary (ALCAPA) is a rare congenital coronary anomaly in which the left main artery arises pulmonary trunk, resulting to right shunt. ALCAPA associated with septal defects and patent ductus arteriosus. The case discussed had secundum atrial defect. Sudden cardiac death feared complication. We discuss hemodynamics of this shunt combination outline its manage...

Displacement of distal ventriculo-atrial (VA) shunt is not uncommon. However, misplacement of the distal catheter of VA shunt in the internal jugular vein is a possibility, especially when conducted without intraoperative monitoring. We describe a patient in whom a VA shunt was performed due to failure of ventriculo-peritoneal shunt and the distal catheter of the shunt was found to be misplaced...

patients with coronary artery disease and left ventricular dysfunction have high mortality with non surgical (medical) treatment. coronary artery bypass grafting improves survival and the quality of life. recently, revascularization without cardiopulmonary bypass has been presented as a viable alternative. the aim of this study was to survey the result of coronary artery bypass grafting with of...