The traditional approach to the ECG diagnosis of left ventricular hypertrophy (LVH) is focused on the best estimation of left ventricular mass (LVM) i.e. finding ECG criteria that agree with LVM as detected by imaging. However, it has been consistently reported that the magnitude of agreement is rather low as reflected in the low sensitivity of ECG criteria. As a result, the majority of cases w...

BACKGROUND Fibroblast growth factor 23 (FGF23), with its co-receptor Klotho, plays a crucial role in phosphate metabolism. Several recent studies suggested that circulating FGF23 and α-Klotho concentrations might be related to cardiovascular abnormalities in patients with advanced renal failure. PURPOSE Using data from 100 cardiology inpatients who were not undergoing chronic hemodialysis, th...

Children with developmental coordination disorder (DCD) are more likely to develop cardiovascular disease (CVD) risk factors such as obesity and reduced cardio-respiratory fitness. It has also been shown that adolescents with probable DCD (p-DCD) have elevated cardiac output (CO) and stroke volume (SV) compared to typically developing (TD) controls, which in turn may heighten their risk of deve...

Background Left ventricular mass (LVM) quantification by cine-CMR is typically performed by planimetry of contiguous LV short axis images. This approach relies on use of anatomic landmarks or quantitative binary cutoffs to define the basal-most aspect of the LV. Methodological discordance concerning criteria for LV basal slice selection has the potential to alter cine-CMR quantified LVM. This s...

The ability to measure left ventricular mass (LVM) by echocardiography has led to an important understanding of the contribution of inappropriate LVM to the pathogenesis of cardiovascular disease. In particular, the identification by Levy et al, in the Framingham Study, of increased LVM as a risk factor for cardiovascular morbidity and mortality independent of conventional risk factors, includi...

Background Left ventricular mass (LVM) is widely used to guide clinical decision-making. CMR is well suited to measure LVM as it provides high-resolution delineation of myocardial contours. CMR quantification of LVM is typically performed via planimetry of contiguous short axis images, an approach fundamentally dependent on reader selection of short axis images to be contoured. Established meth...

patients and methods twenty-two young men (age = 23.34 ± 2.56 years, weight = 72.47 ± 12.01 kg, and height = 174.10 ± 5.75 cm) were recruited and randomly assigned into control (n = 10) and hiit (n = 12) groups. echocardiography was used to evaluate left ventricular mass (lvm), end-systolic volume (esv), end-diastolic volume (edv), interventricular septal wall thickness (ivswt), stroke volume, ...

BACKGROUND The cardiac renin-angiotensin system has been suggested to be involved in the development of left ventricular hypertrophy. In humans, a strong correlation has been found between plasma angiotensin I-converting enzyme (ACE) activity and the insertion/deletion (I/D) polymorphism of the ACE gene, which has been reported to be associated with myocardial infarction, ischemic and idiopathi...

Twenty-four patients with aortic valve disease were studied before and 19+/-12 months following valve replacement with a well functioning prosthesis. Biplane left ventricular angiography and pressures were utilized to determine end-diastolic volume/m2 (EDV), end-systolic volume/m2 (ESV), ejection fraction (EF), left ventricular mass/m2 (LVM) and stroke work (SW). There were nine patients with a...

ECG criteria for left ventricular hypertrophy (LVH) were mostly validated using left ventricular mass (LVM) as measured by M-mode echocardiography. LVM as measured by cardiac MRI has been demonstrated to be much more accurate and reproducible. We reevaluated the sensitivity and specificity of 4 ECG criteria of LVH against LVM as measured by cardiac MRI. Patients with systemic hypertension (n=28...