نتایج جستجو برای: leptomeningeal metastasis
تعداد نتایج: 133009 فیلتر نتایج به سال:
Metastatic leptomeningeal carcinomatosis is estimated to occur in 3% to 8% of solid carcinomas. The most common causes of leptomeningeal carcinomatosis are breast cancer, lung cancer and malignant melanoma. Leptomeningeal carcinomatosis associated with gastric cancer, especially in its early stages, is exceedingly rare. Its presenting symptoms include headache, nausea and seizures. In this repo...
Risk or presence of metastasis in medulloblastoma causes substantial treatment-related morbidity and overall mortality. Through the comparison of cytokines and growth factors in the cerebrospinal fluid (CSF) of metastatic medulloblastoma patients with factors also in conditioned media of metastatic MYC amplified medulloblastoma or leptomeningeal cells, we were led to explore the bioactivity of ...
We describe a case of spinal leptomeningeal metastases of an astrocytoma of the conus medullaris that presented with quadriplegia. The patient was a 50-year-old woman with a previously treated astrocytoma of the conus medullaris and a spinal cord metastasis at the Th2-L level. Four years after the initial treatment, the patient developed weakness of the upper extremities with a decreased muscul...
We present the case report of a twenty-five-year-old Moroccan male patient who suffered from leptomeningeal carcinomatosis related to a signet-ring cell carcinoma of the rectum. He presented to the emergency department with abdominal pain, constipation, weight loss and rectal bleeding. The rectal examination showed a rectal tumor and a CT scan revealed a large bowel obstruction due to rectal di...
Leptomeningeal carcinomatosis occurs in approximately 5% of patients with cancer. The most common cancers involving the leptomeninges are breast, lung cancer and melanoma. However, gastric adenocarcinoma has been rarely reported with leptomeningeal carcinomatosis. The presenting manifestations are usually headache, visual disturbances and seizures. We report a case of leptomeningeal metastasis ...
Abstract Medulloblastoma is a molecularly heterogenous brain tumor of the cerebellum and leading cause pediatric cancer mortality due to its propensity for leptomeningeal metastasis. Leptomeningeal metastasis occurs in over 20-30% patients despite age- risk- adapted chemoradiation therapy. The mechanisms responsible medulloblastoma therapy resistance remain incompletely understood. leptomeninge...
We present a case of leptomeningeal metastases in a 30-year-old man with an extragonadal germ cell tumor. The patient was referred to our hospital for treatment of an occipital brain metastasis. This lesion was resected, followed by whole brain radiotherapy and further chemotherapy, and a temporary complete remission was achieved. However, leptomeningeal recurrence developed, and despite salvag...
In this retrospective study, 47 patients with clinical diagnosis of central nervous system metastases of breast cancer were evaluated by computerized tomography (CT), magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) examination. The patients were divided in 2 groups: 1, without leptomeningeal neoplasm and 2, with leptomeningeal neoplasm. In the group 2, the time interval between t...
Leptomeningeal Carcinomatosis as an Initial and Sole Manifestation of Papillary Renal Cell Carcinoma
Inroduction: Leptomeningeal carcinomatosis (LMC) is an infrequent and devastating complication of systemic malignancy. Although it occurs in 5 – 20% of patients with metastatic cancer, its association with papillary renal cell carcinoma (RCC) is extremely rare. To the best of our knowledge, there are only 3 published case reports of leptomeningeal metastasis occurring in patients with papillary...
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