BACKGROUND Lichen planopilaris (LPP) and its variant frontal fibrosing alopecia (FFA) are primary lymphocytic cicatricial alopecias for which there is no evidence-based therapy. OBJECTIVE We assessed the efficacy of hydroxychloroquine in active LPP and FFA using the LPP Activity Index (LPPAI), a numeric score that allows quantification of the symptoms and signs of the condition for statistica...

Objective: To compare the histopathological findings in horizontal and vertical sections in cases of alopecia with their clinicopathological correlation. Materials and methods: A study of 50 patients was conducted to study the histopathological findings in horizontal and vertical sections in cases of alopecia along with their clinicopathological correlation. Results: In our study, major causes ...

Frontal fibrosing alopecia is a distinctive form of scarring alopecia considered to be a clinical variant of lichen planopilaris. It predominantly occurs in postmenopausal women and has a slowly progressive course. It was first described by Kossard in 1994. Since then the number of reported cases has increased significantly. Coexistence of frontal fibrosing alopecia and autoimmune disorders - s...

Background: The aim of this study was to investigate the thyroid function status in patients with lichen lanopilaris.Methods: In this case control study, 26 (8 male and 18 female) consecutive lichen planopilaris patients, and 36 age and sex matched controls were evaluated for thyroid function status.Results: The median antithyroglobulin serum level was higher in patients than controls (47.1 IU/...

BACKGROUND Lichen planopilaris (LPP) is an inflammatory disease characterized by a lymphomononuclear infiltrate surrounding the isthmus and infundibulum of the hair follicle of the scalp, that evolves into atrophic/scarring alopecia. In the active phase of the disease hairs are easily plucked with anagen-like hair-roots. In this study we focused on the expression of integrins and basement membr...