background: lichen planus is a skin disease that rarely involves mucus membrane. case: in this study, we introduced a rare case of lichen planus of the right vocal cord in a 51- year -old male presented with hoarseness. the lesion started two years ago and the hoarseness became progressive. there were not any lesions found in his buccal mucosa and skin. the biopsy of the lesion showed lichen pl...

OBJECTIVES The purpose of this study was to evaluate the expression of cdk4 and p16, the proteins implicated in hyperproliferation and arrest in oral lichen planus and to compare their expression in erosive and non-erosive oral lichen planus and with normal mucosa and oral squamous cell carcinoma. MATERIAL AND METHODS Analysis of cdk4 and p16 expression was done in 43 erosive oral lichen plan...

AIM To determine the presence of circulating autoantibodies to desmoglein (Dsg) 1 and Dsg 3 in patients with oral lichen planus. METHODS Serum concentrations of circulating autoantibodies to Dsg 1 and Dsg 3 were determined by ELISA in 32 patients with erosive form and 25 patients with reticular form of oral lichen planus, 13 patients with acute recurrent aphthous ulcerations and 50 healthy co...

Background: Lichen planus is a skin disease that rarely involves mucus membrane. Case: In this study, we introduced a rare case of lichen planus of the right vocal cord in a 51- year -old male presented with hoarseness. The lesion started two years ago and the hoarseness became progressive. There were not any lesions found in his buccal mucosa and skin. The biopsy of the lesion showed lichen...

Background: Lichenoid disorders are often difficult to diagnose clinically. Dermoscopy can act as an alternative technique to skin biopsy for diagnosis of various lichenoid dermatoses. Study aim: To study the correlation of dermoscopic with histopathological findings in various lichenoid dermatoses Methods: Fifty patients with clinical picture of lichenoid dermatoses were examined first under t...

OBJECTIVE The aim of this study is to verify whether stratified epithelium-specific antinuclear antibodies are present in the sera of patients with erosive oral lichen planus and cutaneous lichen planus. METHODS We studied the pre-immune and immune serum of a rabbit immunized with a peptide corresponding to the N-terminus of the 70-kDa antigen chronic ulcerative stomatitis protein; sera from ...

BACKGROUND Although oral lichen planus has been classified by the World Health Organization (WHO) as a potentially malignant disorder, such classification is still the target of much controversy. AIM To evaluate the cell proliferation rate in oral lichen planus, comparing it to the rate observed in epithelial dysplasia and oral squamous cell carcinoma, aiming at indications which might indica...

INTRODUCTION Up to 30% of squamous cell carcinomas of the penis arise from a lichen sclerosus, but very few reports in which lichen planus was the preexisting lesion have been published. We report a male with verrucous carcinoma of penis that developed in an area of lichen planus. CLINICAL CASE A 53-year-old male presented with an exophytic tumor on the glans penis that had been present for a...

Lichen planus is a mucocutaneous disease of inflammatory nature and unknown etiology. It is characterized by a cell-mediated immunological response to induced antigenic change in skin and/or mucosa. The possible malignant transformation of lichen planus remains a subject of controversial discussions in the literature. hMSH2 is one of the human DNA mismatch repair (hMMR) genes and it plays an im...