Pleotropic resistant human breast cancer cells (MCF-7), selected for resistance to Adriamycin, were used to study the production of DNA strand breaks by etoposide (VP-16) and its relationship to drug cytotoxicity. It was shown that the resistant MCF-7 cell line was cross-resistant to VP-16, and the degree of resistance was found to be 125-200-fold. Alkaline elution studies indicated that the pa...

the selection of high yielding varieties with good stability‏ ‏is an important objective in rice breeding ‎programs. the grain yield of eight rice lines with a check (nemat) were compared‎‏ ‏on six locations of gilan ‎and mazandaran provinces during two years, using rcbd with four replications. combined analysis of ‎variance showed that the effect of variety and year ‎‏×‏‎ location ‎‏×‏‎ variet...

fcεri, the high affinity receptor for ige plays a critical role in triggering the allergic reactions. it is responsible for inducing mast cell degranulation and deliberation of allergy mediators when it is aggregated by allergen and ige complexes. fcεri on the mast cells consists of three subunits; α chain directly binds ige, β chain and dimmer of γ chains together mediate intracellular signali...

infectious bursal disease (ibd) is an economically important viral disease of chickens with worldwide distribution which suppresses the immune system of young chickens. vp2 is the major host-protective protein of infectious bursal disease virus (ibdv). the encoding region of vp2 protein was pcr amplified from a plasmid containing a cdna fragment of large genomic segment of ibdv, strain d78. thi...

background: the organochlorine ddt has estrogenic activity but the mechanism underlying the estrogenic activity of this pesticide remains unclear. in the present investigation here, we studied the transcriptional effects of a synthetic organochlorine pesticide o,p’-ddt [1.1.1.-trichloro-2-(o-chlorophenyl)-2-p-chloriphenyl ethane] and its metabolite p,p'-dde (2-2-bis(4/chlorophenyl)-1-1-dic...

The updated H-band spectral line list (from \lambda 15,000 - 17,000\AA) adopted by the Apache Point Observatory Galactic Evolution Experiment (APOGEE) for SDSS IV Data Release 16 (DR16) is presented here. APOGEE a combination of atomic and molecular lines with data from laboratory, theoretical, astrophysical sources. Oscillator strengths damping constants are adjusted using high signal-to-noise...

line n-78-14 with the pedigree of sha4/chil cm91099-25y-om-3n-1y-oyz-o10m-oy-3m-o10 was obtained from cimmyt, mexico in 1996 through high rainfall wheat screening nursery. preliminary evaluation of the genotypes in international nursery in gorgan and sari research stations during 1996-97 cropping season, resulted in selection of this line as one of the most high yielding genotypes. selected lin...