نتایج جستجو برای: linked immunospot assay

تعداد نتایج: 428010  

Journal: :Clinical and vaccine immunology : CVI 2006
Sung-Han Kim Sang-Gu Yeo Jae-Hyun Cho Hong-Bin Kim Nam-Joong Kim Myoung-don Oh Kang-Won Choe Youngmee Jee Haewol Cho

We report that vaccine dilution (1:1 or 1:10) and previous vaccinia virus vaccination status had no significant effect on cell-mediated immune responses (i.e., the immediate vaccinia virus-specific gamma interferon-producing T-cell response measured by enzyme-linked immunospot assay) 1 month after smallpox vaccination (Lancy-Vaxina; Berna Biotech, Switzerland).

Journal: :Journal of clinical microbiology 2004
Elisabeth Schölvinck Katalin A Wilkinson Adam O Whelan Adrian R Martineau Michael Levin Robert J Wilkinson

The gamma interferon secretion levels of 52 adults whose T cells had been stimulated with the Mycobacterium tuberculosis antigens CFP-10 and ESAT-6 were measured by enzyme-linked immunospot methods and a whole-blood-based assay. The test results correlated well (r = 0.689, P < 0.0001). Its simple format and use of only small volumes of blood make the whole-blood assay suitable for pediatric pra...

Journal: :Indian Journal of Pharmaceutical Sciences 2021

This study aims to observe and analyze the diagnostic value of T-cell enzyme linked immunospot assay for tuberculosis infection during diagnosis pulmonary extrapulmonary tuberculosis. The objects were 200 cases patients in outpatient department or inpatient our hospital, including 100 with active tuberculosis, Meanwhile, we selected 90 non disease, nontuberculous disease health examination. tes...

Journal: :The Journal of infectious diseases 2013
Lindsey R Baden Stephen R Walsh Michael S Seaman Robert P Tucker Kathleen H Krause Alka Patel Jennifer A Johnson Jane Kleinjan Katherine E Yanosick James Perry Elise Zablowsky Peter Abbink Lauren Peter M Justin Iampietro Ann Cheung Maria G Pau Mo Weijtens Jaap Goudsmit Edith Swann Mark Wolff Hayley Loblein Raphael Dolin Dan H Barouch

BACKGROUND We report the first-in-human safety and immunogenicity assessment of a prototype Ad26 vector-based human immunodeficiency virus (HIV) vaccine in humans. METHODS Sixty Ad26-seronegative, healthy, HIV-uninfected subjects were enrolled in a randomized, double-blinded, placebo-controlled, dose-escalation phase 1 study. Five groups of 12 subjects received 10(9)-10(11) vp of the Ad26-Env...

Journal: :Clinical chemistry 1995
S M Marcovina J J Albers B Gabel M L Koschinsky V P Gaur

Lipoprotein(a) [Lp(a)] has been measured in numerous clinical and epidemiological studies by a variety of immunochemical methods. However, little, if any, consideration has been given to the confounding effect of the size heterogeneity of apolipoprotein(a) [apo(a)] on the measurement of Lp(a). We developed three direct-binding enzyme-linked immunosorbent assays (ELISAs) with detecting antibodie...

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