malondialdehyde (mda) is widely used as a biomarker for assessing oxidative stress in biomedical fields. lipid peroxidation is a chain phenomenon resulting in the formation of various active compounds that result in cellular damage. biomonitoring of mda has been used in both in-vivo and in-vitro studies as a key biomarker for various disease patterns including hypertension, diabetes, atheroscle...

abstract the objective of present study was to evaluate pharmacokinetic parameters of dibudipine phytosolve after oral administration in rats. the solubility test was carried out to select suitable oily solvent for dibudipine. phytosolve formulation was prepared with a medium chain triglyceride (mct) oil (20%), soybean phospholipids (5%) and a 70% fructose solution (75%). the effect of polyol c...

uterine sarcoma is a rare tumor of mesodermal origin, accounting for 2-6% of uterine malignancies. leiomyosarcoma (lms) has been reported in only 1% of all uterine malignancies and is regarded as the most common primary uterine sarcoma. herein, we present a case of lms with unusual macroscopic features. the patient was a 61-year-old woman with lms, which consisted of a large cystic mass (88×136...

large unilamellar liposomes and multilamellar vesicles consisting of dmpc interacted with cationic phosphorus-containing dendrimers cpds g3 and g4. dsc and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. calorimetric studies indicate that the enthalpy of the transition of the lipids tha...

aloe vera has been used worldwide in pharmaceutical, food and cosmetic industries due to the plethora of biological activities of its constituents. this study was done to evaluate the effects of dietary aloe vera on growth and lipid peroxidation in rainbow trout (oncorhynchus mykiss). a total number of 480 o. mykiss (mean weight 9.50 ± 0.85 g) were randomized into four experimental groups inclu...

the objective of this study was to evaluate effect of different concentrations of catalase in two extenders on motility, viability and lipid peroxidation bull spermatozoa during semen freezing process. thirty ejaculates collected from ten holstein bulls were pooled and evaluated at 37 °c. pool ejaculated was split into two main experimental groups, 1 and 2. in experiment 1, specimen was diluted...

background: this study has been undertaken to find out the possible radioprotective potential of the alstonia scholaris extract (ase). materials and methods: for experimental study, healthy swiss albino male mice were selected from an inbred colony and divided in four groups. group i (normal) did not receive any treatment. group ii was orally supplemented ase once daily at the dose of 100 mg/ k...

objective: this study was designed to investigate the antinociceptive effect of curcumin in diabetic rats by using the formalin and hot tail immersion tests. methods: wistar rats were divided into the following six groups:  control; curcumin-treated control (50 mg/kg); diabetic; sodium salicylate (ss)-treated diabetic; and two curcumin-treated diabetic groups (10 and 50 mg/kg). curcumin was ad...

pythium irregulare oomycetes adapts with environmental changes including crude oil concentration by changing the composition of lipids in the cytoplasmic membrane and providing the required characteristics for adaptation in improper and stressful environmental situations. it was found that cultivation of pythium irregulare lx oomycetes in the nutrient media with different concentrations of crud...