Pea (Pisum sativum) roots were treated with aluminum in a calcium solution, and lipid peroxidation was investigated histochemically and biochemically, as well as other events caused by aluminum exposure. Histochemical stainings were observed to distribute similarly on the entire surface of the root apex for three events (aluminum accumulation, lipid peroxidation, and callose production), but th...

Lipid peroxidation in vitro in rat liver microsomes (microsomal fractions) initiated by ADP-Fe3+ and NADPH was inhibited by the rat liver soluble supernatant fraction. When this fraction was subjected to frontal-elution chromatography, most, if not all, of its inhibitory activity could be accounted for by the combined effects of two fractions, one containing Se-dependent glutathione (GSH) perox...

objective(s):hypoxia induces cellular oxidative stress that is associated with neurodegenerative diseases. here, the protective effects of ferulic acid (fa) on hypoxia-induced neurotoxicity in pc12 cells were evaluated. materials and methods:we investigated the effect of fa on pc12 cells subjected to hypoxia stress, in vitro. results:fa increased cell viability, prevented membrane damage (ldh r...

welsh onion (allium fistulosum l.) is one of the important vegetable crops in china. however, the seeds of this crop are short-lived and their vitality tends to be easily lost in the course of storage. the present study was conducted to elucidate the effects of welsh onion seed priming with potassium nitrate (kno3) on seed vigor and on other such related mechanisms during twelve months of stora...

Effects of S-allylcysteine (SAC), an organosulfur compound of garlic, on circulatory lipid peroxidation and antioxidant levels were evaluated in N-nitrosodiethylamine (NEDA)-induced hepatocarcinogenesis in Wistar rats. Significantly elevated thiobarbituric acid reactive substances in the circulation of rats bearing carcinoma indicated the higher levels of lipid peroxidation which was accompanie...

Pathogenic Th2 cells are key mediators of type-2-driven skin disease. Current treatments inhibit the activation pathogenic or neutralize their effector molecules. Yet, therapies targeting long-term survival in missing. Th9 a subset IL-9-expressing Th that share overlapping features with cells. Therefore, better characterization is utmost importance to identify regulators cell specifically expre...

Present study was designed to compare antioxidant and DNA damage protection of Soxhlet assisted (80% methanol) extract (SEMC) with microwave assisted (80% methanol) extract of Michelia champaca Linn. (MEMC). The in vitro antioxidant activity of SEMC and MEMC were tested for DPPH, hydroxyl radical (OH) by deoxyribose, lipid peroxidation and reducing power capacity. The extracts were also tested ...

Irradiation of sulfonamide derived oral antidiabetic drug, tolazamide (N-[(azepan-1ylamino) carbonyl]-4-methylbenzenesulfonamide, 1) in a phosphate buffered solution under aerobic atmosphere afforded two photoproducts by cleavage of S-N and C (O)-N bonds of urea units. When irradiated with linoleic acid it photoinduced lipid peroxidation. The insignificant decrease in lipid peroxidation test un...

BACKGROUND AND PURPOSE Heme-proteins, besides causing renal tubular obstruction, may contribute to rhabdomyolysis-induced renal injury through a heme-iron-mediated lipid peroxidation process. In the present study, we compared the combined therapy of a lipid peroxidation inhibitor, 21-aminosteroid (21-AS) and fluid-alkaline-mannitol (FAM) diuresis with either of them alone to determine the effic...

The treatment of breast cancer by retinoic acid (RA) may be mediated by lipid peroxidation. Expression of metallothionein (MT) in cancer cells, however, can protect against lipid peroxidation by scavenging hydroxyl radicals. In this study, a two-by-six factorial design was used to investigate the interactive effects of all-trans-RA and zinc (Zn)-induced MT on the growth of two human breast canc...