نتایج جستجو برای: lipid peroxidation lpo

تعداد نتایج: 162309  

Journal: :FEBS letters 1979
A V Putvinsky A I Sokolov D I Roshchupkin Y A Vladimirov

Lipid peroxidation (LPO) of unsaturated fatty acids in bimolecular lipid membranes (BLM), induced by ultraviolet irradiation [l-3] or by chemical agents [4], brings about an increase in conductivity of these membranes. For BLM prepared from egg phosphatidylcholine/cholesterol mixture this effect is accounted for by the rise of proton permeability [3,5]; the maximal conductivity enhancement bein...

Journal: :Free radical biology & medicine 2006
Stephen G Hummel Anthony J Fischer Sean M Martin Freya Q Schafer Garry R Buettner

Nitric oxide (NO*) is an effective chain-breaking antioxidant in free radical-mediated lipid oxidation (LPO). It reacts rapidly with peroxyl radicals as a sacrificial chain-terminating antioxidant. The goal of this work was to determine the minimum threshold concentration of NO* required to inhibit Fe2+ -induced cellular lipid peroxidation. Using oxygen consumption as a measure of LPO, we simul...

2017

The aim of the study was to elucidate the state of lipid metabolism, the processes of lipid peroxidation (LPO) and the state of the antioxidant system (AOS) in pregnant women with metabolic syndrome. A comprehensive examination of pregnant women without pathology was performed, with signs of a metabolic syndrome. Analysis of the data showed that in pregnant women with impaired glucose metabolis...

Journal: :Molecular Vision 2007
Tzvete Dentchev Yuemang Yao Domenico Praticó Joshua L. Dunaief

PURPOSE A number of studies have suggested that retinal light damage involves oxidative stress. These include demonstration of protection by antioxidants, immunohistochemical detection of oxidative stress markers, and upregulation of antioxidant enzymes. Recently a new specific marker of lipid peroxidation (LPO), isoprostane F(2alpha)-VI, has been developed. This prostaglandin isomer is produce...

Amina Karimiania, Efaht Souri, Mehrali Mahmood Janlow, Sussan Ardestani k,

In order to find a prophylactic supplementation for individuals who are at risk of exposure to ionizing radiation, we attempted to evaluate the effect of Vitamin E (Vit-E), a biological free radical scavenger, on restoration of hepatic lipid peroxidation (LPO) and lipid profile (LP) changes induced by sublethal g- radiation in BALB/c mice. The concentrations of cholesterol and phospholipid were...

Journal: :International journal of experimental diabetes research 2002
Randall L. Davis Christy L. Lavine Melissa A. Arredondo Patrick McMahon Thomas E. Tenner, Jr.

Determination of reliable bioindicators of diabetes-induced oxidative stress and the role of dietary vitamin E supplementation were investigated. Blood (plasma) chemistries, lipid peroxidation (LPO), and antioxidant enzyme activities were measured over 12 weeks in New Zealand White rabbits (control, diabetic, and diabetic + vitamin E). Cholesterol and triglyceride levels did not correlate with ...

Journal: :Free radical research 2010
Anne Negre-Salvayre Nathalie Auge Victoria Ayala Huveyda Basaga Jordi Boada Rainer Brenke Sarah Chapple Guy Cohen Janos Feher Tilman Grune Gabriella Lengyel Giovanni E Mann Reinald Pamplona Giuseppe Poli Manuel Portero-Otin Yael Riahi Robert Salvayre Shlomo Sasson Jose Serrano Ofer Shamni Werner Siems Richard C M Siow Ingrid Wiswedel Kamelija Zarkovic Neven Zarkovic

Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review. New data and literature review are provided evaluating the role of LPO in the patho...

Journal: :The Journal of endocrinology 2000
R Shinohara T Mano A Nagasaka R Hayashi K Uchimura I Nakano F Watanabe T Tsugawa M Makino H Kakizawa M Nagata K Iwase Y Ishizuki M Itoh

Free radicals, hydroxyperoxides and H(2)O(2) are all known to damage cell components. This study was designed to compare the concentrations of hydroxyperoxide and free radical scavengers in the cardiac muscles of old rats in the hyper- or hypothyroid condition, to determine whether rates of peroxidation would differ with age, thyroid status, or both. Rats were rendered hyper- or hypothyroid by ...

Journal: :The Journal of clinical endocrinology and metabolism 2012
Alliny S Bastos Dana T Graves Ana Paula de Melo Loureiro Carlos Rossa Júnior Dulcinéia Saes Parra Abdalla Tanize do Espírito Santo Faulin Niels Olsen Câmara Oelisoa M Andriankaja Silvana R P Orrico

CONTEXT Periodontitis is the most common lytic disease of bone and is recognized as a common complication of diabetes. Lipid peroxidation (LPO) is increased in diabetes and may be related to modulation of the inflammatory response. LPO levels in patients with diabetes and periodontal disease have not been evaluated. OBJECTIVE The aim of this study was to evaluate the levels of LPO and its cor...

2016
Md Wasim Khan

Submit Manuscript | http://medcraveonline.com MOJ Toxicol (2016), 2(1): 00026 Abbreviations: RPM: Revolutions Per Minute; AST: Serum Aspartate Aminotransferase; ALT: Serum Glutamate Pyruvate Transaminase; Scr: Serum Creatinine; BUN: Blood Urea Nitrogen; C: Control; V: Venom; VC : Vitamin; VVC: Venom+Vitamin C ; TBS :Tris Buffered Saline; SOD: Superoxide Dismutase; Cat: Catalase; GSH-Px: Glutath...

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