Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system that contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid-Based Nanosystem is introduced as biocompatible, non-toxic, safe nano-drug compared to polymeric or metallic nanoparticles. Due its safety, stability, high loading capacity other lipid-based nanocarriers, NLC gained ...

The two main applications of silica-based materials in medicine and biotechnology, i.e. for bone-repairing devices and for drug delivery systems, are presented and discussed. The influence of the structure and chemical composition in the final characteristics and properties of every silica-based material is also shown as a function of the both applications presented. The adequate combination of...

bioactive products from snail slime of “helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. however, the poor pharmacokinetics characteristics of these natural compounds limit their use. nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug delivery sys...

background and aims. a carious lesion is the accumulation of numerous episodes of de- and remineralization, rather than a unidirectional demineralization process. tooth destruction can be arrested or reversed by the frequent delivery of fluoride or calcium/phosphorous ions to the tooth surface. the present study compared and evaluated the remineralization potential of sodium fluoride and bioact...

Type 2 diabetes mellitus (T2DM) is a major chronic disease that is prevalent worldwide, and it is characterized by an increase in blood glucose, disturbances in the metabolism, and alteration in insulin secretion. Nowadays, food-based therapy has become an important treatment mode for type 2 diabetes, and phytobioactive compounds have gained an increasing amount of attention to this end because...

Albumin is playing an increasing role as a drug carrier in the clinical setting. Principally, three drug delivery technologies can be distinguished: coupling of low-molecular weight drugs to exogenous or endogenous albumin, conjugation with bioactive proteins and encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in solid tumors forms the rationale for developing alb...

the water content of the epidermis is a main factor in maintaining skin smoothness and elasticity and preventing skin dryness. occlusive products can greatly affect skin hydration by forming a barrier on the skin following the topical administration of oil-based formulations. these products repair the skin barrier by restoring the skin lipids as well. solid lipid nanoparticles (slns) have recen...

Diets rich in carotenoids have been correlated with a reduced risk of developing certain types of chronic diseases, but these bioactive components have low intestinal absorption due to their hydrophobic nature. The aim of this work was to study the effect of carrier oil composition (medium-chain triglyceride (MCT) to long-chain triglyceride (LCT) ratio) and total carrier oil concentration (1% o...

Bioactive products from snail slime of “Helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. However, the poor pharmacokinetics characteristics of these natural compounds limit their use. Nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug del...