background vitamin d deficiency is believed to cause variety of abnormalities such as liver stiffness and fibrosis. it is also shown that vitamin d deficiency may result in chronic liver disease or liver cirrhosis. in this study, we aimed to systematically review the literature wherein the relationship between vitamin d deficiency and the severity of chronic liver disease or liver cirrhosis had...

the incidence of cirrhosis and primary hepatic carcinoma in the autopsy material is studied. in 4389 autopsies performed, during the last 9 years we found 134 (3%) cases of cirrhosis and 24 (0.5%) cases of primary hepatic carcinoma. the majority of the patients were from northwest and west part of the city. of the 134 cases of cirrhosis 90 correspond to the portal type, 24 to the post-necrotic ...

results roc-derived spo2 threshold of ≤ 94% can predict hypoxemia (pao2 < 60 mmhg) with a sensitivity of 100% and a specificity of 95%. furthermore, there are associations between the roc-derived spo2 threshold of ≤ 97% and detection of hypoxemia (pao2 < 70 mmhg) with a sensitivity of 100% and a specificity of 46%. the accuracy of pulse oximetry was not affected by the severity of liver disease...

background hepatic fibrosis is an inclusion indicator for treatment and a major independent predictor of treatment response in patients with chronic hepatitis c. liver biopsy, considered as the “gold standard” for evaluating liver fibrosis, has carried some drawbacks. currently used noninvasive predictors of fibrosis are considered less accurate than liver biopsy. objectives our aim was to asse...

conclusions patients with chronic hepatitis c and with a ciscun ≤ 1 had a very low rate of cirrhosis while those with a ciscun = 4 had a high risk of cirrhosis. patients with ciscun = 2 or 3 had an intermediate rate of cirrhosis, and therefore needed to perform a liver biopsy to receive a reliable diagnosis. results we enrolled 249 patients who had complete laboratoristic data, and sufficient l...

background hepatitis b virus (hbv) is among the leading causes of liver cirrhosis worldwide. predictors of cirrhosis in iranian chronic hepatitis b (chb) patients are yet to be clearly identified. objectives evaluating the predictive factors of liver cirrhosis in chb. patients and methods a longitudinal study was conducted during 1995 - 2014 on all chb patients who were referred to tehran hepat...

discussion the disappearance of olp might be due to immunosuppressive therapy following liver transplantation. further observations and studies are necessary to clarify the relationship between olp and pbc. case presentation we describe a case of oral lichen planus (olp) accompanied with pbc that resolved following liver transplantation 14 years later. this patient received immunosuppressive dr...

background the fas receptor/ligand system including soluble forms is the most important apoptotic initiator in the liver. dysregulation of this pathway may contribute to abnormal cell proliferation and cell death and is regarded as one of the mechanisms preventing the immune system from rejecting the tumor cells. objectives to analyze the role of fas system fas/ fas ligand (fas/ fasl) in the mu...

background reversibility of advanced fibrosis after hcv-clearance is an important goal of therapy. objectives measuring liver stiffness (ls) by transient elastography (te) might be helpful in this setting. patients and methods we evaluated 104 patients with biopsy-proven chronic hepatitis c (chc) and sustained virological response (svr) after peg-interferon (ifn) plus ribavirin since at least 1...