background & objectives: chronicity of lupus nephritis (ln) should be considered for interaction of cell mediated immunity (cmi) and dendritic cells in glomeruli and tubulointerstitial areas. in this study establishment of immunohistopathological changes of dendritic cells and other immune effector cells in lupus nephritis comparing with non-lupus nephritis was performed. materials & m...

background: dendritic cells (dcs) are the most potent stimulators of primary t cell responses and play a key role in immune reactions after stem cell transplantation. very little is known about the cord blood (cb) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after cb transplantation.   objectives: the aim of this stud...

dendritic cells (dcs) are professional antigen presenting cells that have a potential role in the initiating of immune responses. the cell vaccination is a new strategy in treatment of infectious diseases and cancers. in this study, we have generated monocyte-derived dendritic cells of lymphoma patient's peripheral blood mononuclear cells then; these cells were used as vaccine in lymphoma patie...

follicular dendritic cells or dendritic reticulum cells are important components of the immune system essential for antigen presentation. malignancies arising from these cells are uncommon and the first case was reported in 1986. the most common sites of follicular dendritic cell sarcomas are lymph nodes, especially cervical, axillary and mediastinal regions, but extranodal sites including head...

conclusions artemisia absinthium l. extract, at concentrations below 100 µg/ml, can modulate the immune response toward a th1 pattern, by induction of cd40 expression on dcs and cytokine production. also, it can inhibit dcs t cell stimulating activity, at high concentrations. therefore, the traditional use of this plant possibly modulates immune-mediated disorders. however, future studies are n...

background: dendritic cells (dcs) play a central role in the initiation and expansion of t cell mediated immune responses with potential immunotherapy application. the compounds which have the ability to induce immunomodulatory effects on dcs may be employed for the treatment of immunopathologic conditions such as autoimmune diseases. objective: the aim of this study was to investigate the in v...

background: the use of dendritic cells (dcs) as a cellular adjuvant provides a promis-ing approach in immunotherapy of cancer. it has been demonstrated that listeria mono-cytogenes activated dcs pulsed ex vivo with tumor antigens trigger a systemic th1-biased specific immune response and a single dose of this vaccine will cause a consider-able anti tumor immunity. objective: the present study w...