BACKGROUND To assess the detection rate of liver lesions in patients with advanced gastroenteropancreatic neuroendocrine carcinomas (GEP-NETs) using echo planar (EP) DWI (diffusion weighted imaging) as compared to standard FSE T2 wi and FFE T1 wi with i.v. (Gd-EOB)-DTPA. MATERIAL/METHODS This prospective single-institution study included 55 patients with liver involvement confirmed by GEP-NET...

Background: Iron accumulation in organs such as heart and liver can cause morbidity and mortality in transfusion-dependent patients with β-thalassemia major. MRI T2* relaxometry has been increasingly used in clinical practice for quantitative assessment of iron overload in heart and liver. For a heavily iron loaded liver, T2* is ultra-short (<1ms). In this scenario, conventional gradient echo s...

OBJECTIVE To evaluate the diagnostic value of T2* mapping using 3D multi-echo Dixon gradient echo acquisition on gadoxetic acid-enhanced liver magnetic resonance imaging (MRI) as a tool to evaluate hepatic function. MATERIALS AND METHODS This retrospective study was approved by the IRB and the requirement of informed consent was waived. 242 patients who underwent liver MRIs, including 3D mult...

Purpose: To improve liver iron load assessment by investigating the precision of different approaches of T2 Measurement. Background: Iron overload is a major problem in the treatment of thalassemic patients. Liver iron concentration (LIC) is an important index toward the management of body iron load. The accuracy of iron load estimation may suffer from the methodology of T2 measurement and ther...

background: to retrospectively describe imaging characteristics of liver metastases on fused fdg-pet/ mri data sets and to compare the diagnostic accuracy of mri and fused fdg-pet/mri data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. materials and methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by fdg-pet/ct and l...

OBJECTIVE To assess the value of applying MultiVane to liver T2-weighted imaging (T2WI) compared with conventional T2WIs with emphasis on detection of focal liver lesions. MATERIALS AND METHODS Seventy-eight patients (43 men and 35 women) with 86 hepatic lesions and 20 pancreatico-biliary diseases underwent MRI including T2WIs acquired using breath-hold (BH), respiratory-triggered (RT), and M...

Close monitoring of liver iron content is necessary to prevent iron overload in transfusion-dependent anemias. Liver biopsy remains the gold standard; however, MRI potentially offers a noninvasive alternative. Iron metabolism and storage is complicated and tissue/disease-specific. This report demonstrates that iron distribution may be more important than iron speciation with respect to MRI sign...

RATIONALE FOR THE STUDY This cross-sectional multicenter study was conducted to investigate any difference in liver stiffness measurements (LSM), evaluated by transient elastography, between patients affected by β thalassaemia major, with and without hepatitis C virus (HCV) infection, and healthy blood donors (controls). Secondary aim was to assess any correlation between transient elastography...

Abstract Background Iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. Severe iron deposition in tissues leads to organ dysfunction. Many organs can be affected such as heart, liver, and endocrine organs. Cardiac failure and liver fibrosis are the consequent of Iron overload in transfusion dependent hemoglobinopathy. Magne...

Abdullah H, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-219793 Description Conjoined twins are very rare with incidence of 1 per 250 000 live births. Fetal MRI is an important adjunct to ultrasound particularly in evaluation of complex fetal anomalies and organ positions. 3 This case report illustrates our first experience in MRI fetal of conjoined twins with the current available sequences....