نتایج جستجو برای: liver protection
تعداد نتایج: 500048 فیلتر نتایج به سال:
Ischemia and reperfusion significantly contributes to the morbidity and mortality of liver surgery and transplantation. Based on studies showing a critical role for adenosine signaling in mediating tissue adaptation during hypoxia, we hypothesized that signaling events through adenosine receptors (ADORA1, ADORA2A, ADORA2B, or ADORA3) attenuates hepatic ischemia and reperfusion injury. Initial s...
Numerous liver diseases are associated with extensive oxidative tissue damage. It is well established that Wnt/β-catenin signaling directs multiple hepatocellular processes, including development, proliferation, regeneration, nutrient homeostasis, and carcinogenesis. It remains unexplored whether Wnt/β-catenin signaling provides hepatocyte protection against hepatotoxin-induced apoptosis. Condi...
Implication for health policy/practice/research/medical education: Liver surgery and perioperative care of patients with hepatic dysfunction is still moving toward better safety. Anesthesiologists play their role with judicious selection of anesthetic medications. Ischemic liver injury occurs in a variety of clinical settings such as trauma, shock, and liver surgery (1, 2). Isch-emia and subseq...
BACKGROUND Drugs to protect the liver are frequently prescribed in some countries as part of treatment for tuberculosis. The biological rationale is not clear, they are expensive and may do harm. We conducted a systematic review to a) describe the ingredients of "liver protection drugs"; and b) compare the evidence base for the policy against international standards. METHODS We searched inter...
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