Lameness is one of the most significant endemic disease problems facing the dairy industry. Claw horn lesions (principally sole hemorrhage, sole ulcer, and white line disease) are some of the most prevalent conditions. Despite the fact that thousands of animals are treated for these conditions every year, experimental evidence is limited on the most effective treatment protocols. A randomized, ...

Lameness in cattle is a health issue where gait is modified to minimise pain. Cattle are currently visually assessed for locomotion score, which provides the degree of lameness for individual animals. This subjective method is costly in terms of labour, and its level of accuracy and ability to detect small changes in locomotion that is critical for early detection of lameness and associated int...

BACKGROUND The Injury Severity Score (ISS) is a widely accepted method of measuring severity of traumatic injury. A modification has been proposed--the New Injury Severity Score (NISS). This has been shown to predict mortality better in adult trauma patients, but it had no predictive benefit in pediatric patients. The aim of this study was to determine whether the NISS outperforms the ISS in a ...

Objective and consistent assessment of locomotion recovery remains challenging in rodent spinal cord injury (SCI). We, therefore, studied the validity relevance CatWalk XT® gait analysis as a tool for assessing functional outcome clinically relevant cervical SCI model rats. In total, 20 Wistar rats were randomly assigned to either C6 clip compression/contusion or sham laminectomy. Locomotion wa...

the mesolimbic dopamine (da) system contains both d1-like and d2-like receptors, has been connected to control of locomotor behavior. an apparent role for d1 and d2 receptors throughout the mesolimbic system in the alteration of locomotor behavior has been demonstrated in pharmacological studies. the nucleus accumbens (nac) is comprised of a core and a shell subregion, which is a component of t...