Hedgehog proteins are intercellular long-range signaling molecules that spread within tissues and activate gene expression during development. Vyas et al. (2008) propose that Hedgehog forms nanometer-sized oligomers that localize in proteoglycan-rich clusters at the surface of cells expressing Hedgehog. This nanoscale organization and enrichment in clusters ensures that Hedgehog is able to spre...

Lagomorpha is a clade of herbivorous mammals nested within Euarchontoglires, one the major placental groups represented today. It comprises two extant families with markedly different body plans: long-eared and long-limbed Leporidae (hares rabbits) short-eared short-limbed Ochotonidae (pikas). These lagomorph lineages diverged probably during latest Eocene/early Oligocene, but it unclear whethe...

Forest roosting bats use a variety of ephemeral roosts such as snags and declining live trees. Although conservation of summer maternity habitat is considered critical for forest-roosting bats, bat response to roost loss still is poorly understood. To address this, we monitored 3 northern long-eared bat (Myotis septentrionalis) maternity colonies on Fort Knox Military Reservation, Kentucky, USA...

In western United States, both mine reclamations and renewed mining at previously abandoned mines have increased substantially in the last decade. This increased activity may adversely impact bats that use these mines for roosting. Townsend’s big-eared bat (Corynorhinus townsendii) is a species of conservation concern that may be impacted by ongoing mine reclamation and renewedmineral extractio...