نتایج جستجو برای: long non coding rna

تعداد نتایج: 2282885  

Journal: :International Journal of Molecular Sciences 2019

Journal: :International journal of clinical and experimental medicine 2015
Xiao-Bo Guo Zhu Hua Chen Li Li-Pan Peng Jing-Shen Wang Bo Wang Qiao-Ming Zhi

The purpose of this study was to determine the expression of long non-coding RNA (lncRNA) FTX and analyze its prognostic and biological significance in colorectal cancer (CRC). A quantitative reverse transcription PCR was performed to detect the expression of long non-coding RNA FTX in 35 pairs of colorectal cancer and corresponding noncancerous tissues. The expression of long non-coding RNA FT...

2012
Irina V. Novikova Scott P. Hennelly Karissa Y. Sanbonmatsu

Long noncoding RNAs (lncRNAs) play a key role in many important areas of epigenetics, stem cell biology, cancer, signaling and brain function. This emerging class of RNAs constitutes a large fraction of the transcriptome, with thousands of new lncRNAs reported each year. The molecular mechanisms of these RNAs are not well understood. Currently, very little structural data exist. We review the a...

Journal: :research in molecular medicine 0
mahla nazari department of biology, islamic azad university, arsanjan branch, arsanjan, iran mahboobeh nasiri department of biology, islamic azad university, arsanjan branch, university blvd., arsanjan, fars. abbas ghaderi sshiraz institute for cancer research, shiraz university of medical sciences, shiraz, iran

background: bladder cancer (bc) is the most common genitourinary cancer in iranians with an unclear etiopathogenesis. long stress induced non-coding transcript 5 is a member of the 12-member family of long non-coding rnas, which is abundantly expressed in higher proliferative cells, as well as the cell vulnerable to cellular stress in response to chemical carcinogens. as variations in long non-...

Background & Aim: Long non-coding RNAs are regulatory molecules that adjust many vital intracellular processes. MALAT1 is a long non-coding RNA playing a key role in the regulation of intracellular important processes and also involved in biology of various cancers. The purpose of this study was to investigate the functions of MALAT1 and overview of its role in cancer biology. Methods: in this...

Journal: :research in molecular medicine 0
mahla nazari department of biology, islamic azad university, arsanjan branch, arsanjan, iran mahboobeh nasiri department of biology, islamic azad university, arsanjan branch, university blvd., arsanjan, fars. abbas ghaderi shiraz institute for cancer research, shiraz university of medical sciences, shiraz, iran

background: bladder cancer (bc) is the most commonly diagnosed genitourinary cancer in iran, presented in both men and women. bc is a multifactorial trait resulting from the complex interaction between several genes and environmental factors. long stress-induced non-coding transcript 5 (lsinct5), a member of the long non-coding rnas, is abundantly expressed in high proliferative cells, as well ...

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