نتایج جستجو برای: low dose interferon
تعداد نتایج: 1503914 فیلتر نتایج به سال:
none of the approved immunomodulatory drugs in adults multiple sclerosis (ms) patients have been officially approved for the pediatric patients and are currently used off-label in this population. in this study, we evaluated the effectiveness and tolerability of intramuscular interferon beta1-a (avonex®) and subcutaneously injected interferon beta1-b (betaferon®) in children with definite relap...
Background and Aims: Interferon alpha is an effective cytokine in viral infections, where it has various roles in immune function. The use of this antiviral agent in the treatment of viral infections and even cancers is common, although, the beneficial effects of this antiviral agent in high doses can be associated with side effects that limit its use. In this project, we tried to investigate t...
Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in Russian Federation, its has not been studied before. The aim this study was to determine interferon drugs, with without it. included cytotoxicity assays preparations, when stored according instructions at 2–8°C, after 1 month storage temper...
experimental allergic encephalomyelitis (eae) is considered as the murine model of multiple sclerosis. daidzein a phytostrogenic compound of soy is known to impose immunomodulatory and antioxidative effects. we conducted this study to assess the potential protective and therapeutic effects of daidzein on allergic encephalomyelitis. c57bl/6 mice were induced with allergic encephalomyelitis ...
A limited institution Phase II pilot study was performed using a very low-dose combination of daily s.c. interleukin (IL)-2 with IFN-alpha-2b in patients with advanced renal cancer in an attempt to duplicate or increase the response documented with higher dose schedules without the attendant toxicity profile. We selected a dose of IL-2 with documented immunological activity and combined it with...
Fructose and glucose are often widely used in food processing may contribute to many metabolic diseases. To observe the effects of different doses fructose on human metabolism cellular communication, volunteers were given low, medium, high fructose. Serum cytokines, glucose, lactate, nicotinamide adenine dinucleotide (NADH) enzymes assayed, central carbon pathway networks cytokine communication...
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic-phase chronic myeloid leukemia (CML) who have had no response to interferon alfa. We compared the efficacy of imatinib with that of interferon alfa combined with low-dose cytarabine in newly diagnosed chronic-phase CML. METHODS We randomly assigned 1106 patients to ...
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