Recently, there have been many case-control studies proposed to test for association between haplotypes and disease, which require the Hardy-Weinberg equilibrium (HWE) assumption of haplotype frequencies. As such, haplotype inference of unphased genotypes and development of haplotype-based HWE tests are crucial prior to fine mapping. The goodness-of-fit test is a frequently-used method to test ...

Split liver transplantation (SLT) and living related transplantation (LRT) have been developed following advancements in liver surgery. In experienced hands they can yield results comparable to full organ liver transplantation. They are today a reality which has to be implemented and used more widely. LRT is the best procedure available and should be the method of choice despite the high succes...

We study the possibility of testing local realistic theory (LRT), envisioned implicitly by Einstein, Podolsky and Rosen in 1935, based on the Bell inequality for the correlations in the decay modes of entangled K or B-mesons. It is shown that such a test is possible for a restricted class of LRT, despite the passive nature of decay events and/or the non-unitary treatment of the correlations whi...

BACKGROUND The built environment can constrain or facilitate physical activity. Most studies of the health consequences of the built environment face problems of selection bias associated with confounding effects of residential choice and transportation decisions. PURPOSE To examine the cross-sectional associations between objective and perceived measures of the built environment; BMI; obesit...

Likelihood ratio tests (LRTs) for comparing several independent gamma distributions with respect to shape parameters, scale parameters, and means are derived. The LRT for testing homogeneity of several gamma distributions is also derived. Extensive simulation studies indicate that the null distributions of the LRT statistics for all four problems depend on the parameters only weakly, and for pr...

Light Rail Transit (LRT) is a kind of rail vehicle form which includes from modern tramcars to speed transport. These vehicles go on special road, underground, floor or specific altitude. Today the number of active serving LRT systems in 50 countries is more than 400. Moreover, a forceful increase has been expected for next years. It is clear that this growing up has certain reasons. In this st...

A performance analysis of likelihood ratio test (LRT)-based and generalized likelihood ratio test (GLRT)based array receivers for the detection of a known real-valued signal corrupted by a potentially noncircular interference is considered in this paper. The distribution of the decision statistics associated with the LRT and GLRT is studied. This allows us to give exact closed-form expressions ...

Testing for homogeneity in finite mixture models has been investigated by many authors. The asymptotic null distribution of the likelihood ratio test (LRT) is very complex and difficult to use in practice. In this paper we propose a modified LRT for homogeneity in finite mixture models with a general parametric kernel distribution family. The modified LRT has a χ2-type null limiting distributio...

Bacterial pathogens coordinate virulence using two-component regulatory systems (TCS). The Bordetella virulence gene (BvgAS) phosphorelay-type TCS controls expression of all known protein virulence factor-encoding genes and is considered the "master virulence regulator" in Bordetella pertussis, the causal agent of pertussis, and related organisms, including the broad host range pathogen Bordete...

For a random sample of size n obtained from a p-variate normal population, the likelihood ratio test (LRT) for the covariance matrix equal to a given matrix is considered. By using the Selberg integral, we prove that the LRT statistic converges to a normal distribution under the assumption p/n → y ∈ (0, 1]. The result for y = 1 is much different from the case for y ∈ (0, 1). Another test is stu...