The starting material used for the isolation of a factor which inhibits the hemolytic activity of streptolysin-O is a wateracetone fraction (manufacturer’s name: Cernitin spissum) of a standardized pollen mixture obtained from six plant species: Zea maize, Pinus montana, Secale cereal, Phleum pratense, Alnus glutinosa, and Dactilus glomerata. The mixture is produced for commercial purposes by A...

Macrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities re...

A lymphocyte blastogenesis inhibitory factor (LBIF) has been characterized as an immunoregulatory molecule, especially on the T-lymphocyte proliferation. Using fast protein liquid chromatography-purified LBIF, we examined the effect of LBIF on the proliferation of various 18 tumor cell lines in vitro in comparison with those of interferon-alpha, interferon-gamma, tumor necrosis factor-alpha, tr...

We propose a new phenomenological law for the shape of the spectral lines in the infrared, which accounts for the exponential decay of the extinction coefficient in the high-frequency region, observed in many spectra. We apply this law to the measured infrared spectra of LiF, NaCl, and MgF2, finding good agreement over a wide range of frequencies.