ANA: antinuclear antibody BID: twice a day CLE: cutaneous lupus erythematosus DIL: drug-induced lupus SLE: systemic lupus erythematosus INTRODUCTION Cutaneous lupus erythematosus (CLE), defined as isolated cutaneous lesions without significant systemic involvement, has a reported incidence and prevalence of 4.3 and 73.2 per 100,000, respectively. It occurs more commonly among women with a repor...

OBJECTIVE The goal of the present study was to estimate the risk ratio of herpes zoster among systemic lupus erythematosus patients after disease onset compared with a cohort of patients without systemic lupus erythematosus over a three-year period. METHODS A nationwide population-based cohort study using the National Health Insurance Research Database identified 10,337 new cases of systemic ...

References DINES, D.E., CLAGETT, O.T. & GOOD, C.A. (1967) Nontuberculous pulmonary parenchymal conditions predisposing to spontaneous pneumothorax. Journal of Thoracic and Cardiovascular Surgery, 53, 726. DUBOIs, E.L. (1966) Lupus Erythematosus, p. 172. McGrawHill Book Company Inc., New York Blakiston Division. HOFFBRAND, B.l. & BECK, E.R. (1965) 'Unexplained' dyspnoea and shrinking lungs in sy...

Systemic lupus erythematosus is a multi-system inflammatory disease. The clinical manifestations are diverse. Hepatic manifestation is a rarely seen complication of systemic lupus erythematosus. We report a case of complication of systemic lupus erythematosus presenting as cholestatic hepatitis in a 56-year-old Chinese woman. The cholestatic hepatitis progressed as part of the lupus activity an...

OBJECTIVES To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment. METHODS We included 67 consecutive childhood-onset systemic lupus erythematosus patients [61 women; median age 18 years (range 11-31)], 55 first-d...

Pleural involvement in drug-induced lupus erythematosus is not uncommon. Lupus erythematosus cells were found in vivo in the pleural of an elderly patient who had received procainamide (Pronestyl) hydrochloride (2 gm daily) for nine months. Patients who initially have pleural effusions while receiving drugs capable of inducing lupus erythematosus should have the fluid analyzed for lupus erythem...

Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...

Two children with lupus erythematosus and myelopathy were studied. The first child developed the neonatal lupus erythematosus syndrome associated with transplacentally acquired anti-Ro/SSA antibodies. The cutaneous manifestations of neonatal lupus erythematosus disappeared but a residual myelopathy was confirmed at 16 months of age. The second child developed cutaneous lupus erythematosus at 3 ...

this case report demonstrates fatal gastrointestinal vasculitis as a rare presentation of systemic lupus erythematosus. a 34-year-old woman presented with abdominal pain and diarrhea. anti nuclear antibody was positive and high titre of anti-ds dna antibody was also reported. treatment with corticosteroid and supportive cares were started; however, her condition worsened. eventually, she was co...

hemophagocytic syndrome (hps) is an uncommon manifestation in systemic lupus erythematosus (sle). clinical features of hps include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. hps comprises primary and reactive forms. herein, we describe a case of untreated sle with hps as one of the first manifestations of systemic lupus.