نتایج جستجو برای: lymphatic tumoral cells
تعداد نتایج: 1400556 فیلتر نتایج به سال:
Metastasis, which commonly uses lymphatics, accounts for much of the mortality associated with cancer. The vascular endothelial growth factor (VEGF)-C coreceptor, neuropilin-2 (Nrp2), modulates but is not necessary for developmental lymphangiogenesis, and its significance for metastasis is unknown. An antibody to Nrp2 that blocks VEGFC binding disrupts VEGFC-induced lymphatic endothelial cell m...
The purpose of this study is to explore the function of plasminogen activator inhibitor-1 (PAI-1) during pathological lymphangiogenesis. PAI-1, the main physiological inhibitor of plasminogen activators is involved in pathological angiogenesis at least by controlling extracellular proteolysis and by regulating endothelial cell survival and migration. Protease system's role in lymphangiogenesis ...
Background: Edible mushroom, Pleurotus florida (P.florida) has been used by mankind in ancient times because of its nutritional values and medicinal benefits. Cytotoxicity of fractions isolated from P.florida has been reported. The aim of this study was to isolate some fractions from P.florida and evaluate its cytotoxicity effects on colon cancer cells. Methods: In this basic study, R5, R10...
Objective: The aim of this study was to compare CD10 expression in tumoral and stromal cells of cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) in order to differentiate SCC from BCC in problematic cases. Methodology: Twenty six SCC and 30 BCC cases were retrieved randomly from Al-zahra hospital pathology archive and CD10 expression was determined in tumoral and stromal c...
INTRODUCTION Factors that emerge as crucial participants in tumour invasion and metastases are matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinase (TIMP) inhibitors and cellular adhesion molecules (CD44 and similar molecules). They play important roles in tumour invasion and metastasis in non-small-cell lung carcinomas (NSCLCs). MATERIALS AND METHODS The study was performe...
Introduction: Squamous cell carcinoma of the oral cavity is one of the most important and common types of head and neck malignancy, with an estimated rate of 4% among all human malignancies. The aim of this study was to determine the association between expression of matrix metalloproteinase 2 and 9 and the clinicopathological features of oral squamous cell carcinoma (OSCC). Materials and Met...
detection of bovine leukemia virus antigens can induces humoral immunity in cow were evaluated. fifteen lymph node from infected cows that had positive results in agid and elisa tests for blv and have clinical signs of lymphosarcoma, in addition five lymph node from apparently healthy cows that had negative results in serological tests. after preparation of extract of lymph nodes, all of the sa...
conclusions as l. crispatus and l. jensenni were significantly higher in bv infected women and the cytotoxic effect of l. crispatus on tumoral cervical cells was high, introduction of new probiotics seems necessary. results l. crispatus, l. gasseri, l. iners, l. jensenii, l. acidophilus and l. rhamnosus were the most frequently occurring species in vagina of healthy iranian women. l. crispatus ...
Lymphangiogenesis and the expression of vascular endothelial cell growth factor C (VEGF-C) in tumors have been considered to be causally promoting lymphatic metastasis. There are only a few studies on lymphatic metastasis in immunocompetent allograft mouse models. To study the relationship between VEGF-C-mediated lymphangiogenesis and axillary lymph node metastasis, we used two mouse mammary ca...
A morphometric analysis of tumoral Langerhans cells and activated macrophages was conducted using canine cutaneous tumors (65 cases of canine cutaneous histiocytoma and 7 cases of pyogranuloma). The histiocytic origin of the tumor cells was confirmed using immunohistochemistry. The parameters of the morphometric analysis included cellular and nuclear size and shape and the nuclear:cytoplasmic r...
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