Background and Aim: Intrahepatic cholestasis of pregnancy (ICP) is associated with raised liver enzymes, pruritus elevated fasting total bile acids (TBA) may lead to adverse perinatal outcomes such as preterm birth, meconium-stained liquor, stillbirth, foetal growth restriction etc. The change in inflammatory profile ICP association TBA not known. Methods: Patients (aged >21) confirmed diagnosi...

Chronic lymphocytic leukemia (CIL) of B-cell origin results in the malignant proliferation of small immunoglobulinbearing lymphocytes. There is currently a controversy in the literature regarding both the ability of this leukemic population to differentiate into mature plasma cells. as well as the ability of apparently normal T cells from these patients to regulate allogeneic B-cell differentia...

cycle times were : normal large and medium lymphocytes, 6.8 and 8.2 hr; lymphoma large and medium cells, 7.6 and 20.2 hr. Most normal small lymphocytes were nondividing, but the small lymphocyte population was replaced by division of medium lymphocytes every 3.2 days. Most lymphoma small lymphocytes were also nondividing and possibly had a finite life-span of less than 2 days. In individual lym...

We have investigated the in vitro transformation of lymphocytes that have been frozen and stored at low temperatures. Cells frozen at different times and stored for various times do transform in a reproducible manner when placed in culture with PHA or as one population of the two-way or the one-way MLR. When frozen-stored lymphocytes are cultured with specific antigen or as both partners in the...

Lyme disease, caused by Borrelia burgdorferi, is characterized by the accumulation of lymphocytes and monocytes in the affected tissue. Endothelial cells line the blood vessel walls and control the trafficking of inflammatory leukocytes from the blood into the surrounding tissues. A model of the blood vessel wall, consisting of human umbilical vein endothelial cells (HUVEC) grown on amniotic co...

These experiments describe the preparation of pure marrow-derived lymphocyte suspensions from the thoracic duct of thymectomized, irradiated rats reconstituted with bone marrow cells. The majority of marrow-derived cells were small lymphocytes morphologically indistinguishable from small lymphocytes in thoracic duct lymph of normal donors. Marrow-derived small lymphocytes (B lymphocytes) were a...

the immune responses that develop following epstien-barr virus (ebv) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. to evaluate the immune response, flow cytometric analysis of the peripheral blood of six patients during the acute phase of ebv infection was performed. this analysis revealed a significant increase in the percentages and th...

Immunofluorescence analysis of mammalian lymphocytes using antiserum directed against chicken erythrocyte alpha-spectrin revealed a lymphocyte population in which spectrin antigen was arranged in the form of a discrete cap (hereafter referred to as capped lymphocytes). This subset could be easily distinguished from other lymphocytes in which the spectrin antigen was diffusely distributed near t...

Background and Aim: IPB-D2 chickens are selected from IPB-D1 due to their disease-resistance characteristics. One-way evaluate the strength of a chicken’s immune system is by examining number circulating T lymphocytes. This assessment can be conducted using modern analytic method called flow cytometry which relies on monoclonal antibodies detect relative proportions each cell measure quality qu...