Background: In patients with ST-segment elevation myocardial infarction (STEMI), Primary percutaneous coronary intervention (PCI) is the preferred reperfusion therapy. Timely primary PCI is essential in improving the clinical outcomes of these patients. The aim of this study was to evaluate the factors affecting balloon delay in STEMI treated patients by primary PCI and its relationship with ma...

BACKGROUND Although plaque rupture is responsible for most myocardial infarctions, few high-risk plaques identified by intracoronary imaging actually result in future major adverse cardiovascular events (MACE). Nonimaging markers of individual plaque behavior are therefore required. Rupture occurs when plaque structural stress (PSS) exceeds material strength. We therefore assessed whether PSS c...

BACKGROUND Elevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown. METHODS AND RESULTS Baseline demographics and 2-year MACE were recorded among subjects undergoing nonemergent percutaneous coronary intervention. A total of 332 subjects (66.6±19.5 years, 69.9% male, 25.3%...

BACKGROUND The treatment of an occluded saphenous vein graft (SVG) with percutaneous coronary intervention may encounter major adverse cardiac events (MACE). MACE rates have been reduced significantly by using the embolic protection device (EPD). OBJECTIVES The aim of this study was to clarify the risks and the benefits of embolic protection devices. PATIENTS AND METHODS In a prospective, n...

background: studies have shown controversial effects of obesity on major adverse cardiac events (mace) after percutaneous coronary intervention (pci). we sought to investigate the impact of the body mass index (bmi) on the mid-term outcome following successful pci. methods: between march 2006 and august 2008, 3948 patients underwent successful elective pci in tehran heart center, tehran, iran, ...

AIMS To investigate relationships between glycated haemoglobin (HbA1c) and reported hypoglycaemia and risk of major adverse cardiovascular events (MACE). METHODS The EXAMINE trial randomized 5380 patients with type 2 diabetes (T2DM) and a recent acute coronary syndrome (ACS) event, in 49 countries, to double-blind treatment with alogliptin or placebo in addition to standard of care. We used C...

OBJECTIVE To develop a multivariate prediction model for major adverse cardiac events (MACE) after percutaneous coronary interventions (PCIs) by using the North West Quality Improvement Programme in Cardiac Interventions (NWQIP) PCI Registry. SETTING All NHS centres undertaking adult PCIs in north west England. METHODS Retrospective analysis of prospectively collected data on 9914 consecuti...

Results During a follow-up period of 47.2 21.8 months (range 4 to 82 months), 49 patients experienced major adverse cardiac events (MACE). The difference in ED prevalence between patients with and those without MACE was significant (61.2% vs. 36.4%; p 0.001). Cox regression analysis showed that ED predicted MACE (hazard ratio [HR] 2.1; 95% confidence interval [CI] 1.6 to 2.6; p 0.001). Among pa...

Arterial stiffness is well known to be an important risk factor for cardiovascular events. Although brachial-ankle pulse wave velocity (baPWV) and bilateral blood pressure (BP) in the arms are measured routinely, it is uncertain whether baPWV and the difference in BP between the arms could predict major adverse cardiovascular events (MACE) after elective percutaneous coronary intervention (PCI)...

OBJECTIVES We aimed to evaluate whether pericardial fat has value in predicting the risk of future adverse cardiovascular outcomes. BACKGROUND Pericardial fat volume (PFV) and thoracic fat volume (TFV) can be routinely measured from noncontrast computed tomography (NCT) performed for calculating coronary calcium score (CCS) and may predict major adverse cardiac event (MACE) risk. METHODS Fr...