Rare diseases (RDs) pose a significant set of problems for patients, since their disease and general social and health situation are often not recognized by the medical community and shunned by health insurance. The sheer number of RDs (5000-8000) and the number of patients (6-8% of the population) are challenging for every society. We wanted to get a better understanding of the rare diseases a...

AIM To estimate the absolute risk (%) of 5- and 10-years cardiovascular mortality in Macedonian type 2 diabetes patients based on DECODE model, and the gender difference of the estimated risk. METHODS AND MATERIALS Observational, cross-sectional study including a cohort of 1,404 type 2 diabetes patients; inclusion criteria: aged 25 to 65 years, absence of confirmed arterial disease, history o...

The Macedonian Society of Nephrology, Dialysis, Transplantation and Artificial Organs, the Macedonian Society of Nephrology and the Macedonian Society of Endocrinology and Metabolic Diseases and the general physicians held a one-day meeting on 11 March 2010 at the Macedonian Academy of Sciences and Arts devoted to the prevention and treatment of diabetic kidney disease. In the Republic of Maced...

Clopidogrel is the thienopyridine of choice for prevention of ischemic events and stent thrombosis in patients with atherotrombotic disease. Recent studies suggest that certain genetic variants involving CYP450 system are responsible for wide interindividual variability in treatment response profiles among clopidogrel treated individuals. The aim of this study was to define the prevalence of mo...

Abstract Regulators and policymakers in many developing countries are facing challenges on how to create opportunities for the crypto industry grow, but at same time protect investors consumers. This study aims better understand demographic socio-economic characteristics of adopters their financial behavior. Our advances knowledge within an array recent contributions token economy covers geogra...

ISSUES ADDRESSED Previous research has revealed low levels of mental health service utilisation and widespread discrimination towards people with mental illness in Sydney's Macedonian community. As an extension to a multifaceted community intervention to improve mental health literacy and reduce stigma, a Macedonian-language play was produced. METHODS Qualitative data from earlier studies and...