Three cobalt complexes bearing tunable, redox-active bipyridyl N-heterocyclic carbene (NHC)-based ligands have been studied for electrocatalytic hydrogen evolution from aqueous solutions. The effect of structural modifications to the ligand framework is investigated across catalyst series, which includes a non-macrocyclic derivative (1-Co) and 16-(2-Co) 15-(3-Co) membered macrocycles. A structu...

Abstract Liquid-assisted grinding (LAG) has received wide attention in chemical synthesis field. Here, we reported that LAG provides a smart strategy to build macrocyclic cocrystal (MCC), achieving quick modification. The been assembled by electronegative permethylated pillar[5]arenes (EtP5) and electropositive ligands. We select three ligands with strong electron-deficient groups for preparati...

The synthesis and characterisation of copper(i) complexes, including two crystal structures of the new chiral pyridine-containing macrocyclic ligands (PC-type), and their use as catalysts in asymmetric cyclopropanation reactions are reported.

A net trans C-N reductive elimination reaction is observed from a macrocyclic aryl-Cu(III) complex, and a mechanistic study of this reaction indicates that coordinating ligands play a role in mediating this unusual transformation.

Targeting of extracellular protein–protein interactions (PPI) is emerging as a major application for de novo discovered macrocyclic peptides. Modern discovery platforms can routinely identify peptide ligands capable highly selective modulation signaling pathways; amenability to chemical synthesis and natural modularity peptides additionally provides an avenue their further structural elaboratio...

Abstract A unique family of chiral peraza N 6 ‐macrocyclic ligands, which are conformationally rigid and have a tunable saddle‐shaped cavity, is described. Utilizing their manganese(I) complexes, the first example earth‐abundant transition metal‐catalyzed asymmetric formal anti‐Markovnikov hydroamination allylic alcohols was realized, providing practical access to synthetically important γ‐amin...

A family of group 13 organometallic macrocyclic phthalates [(MMe2)2(μ-O2C)2-1,2-C6H4]2 (where M = Al (1), Ga (2), In (3)) is prepared, and the reactivity of these homologous carboxylates toward various monodentate Lewis bases is investigated. The studies provide the first structurally characterized methylindium [{(Me2In)(μ-O2C)2-1,2-C6H4}{Me2In(THF)}]n (4) and methylaluminum [{(Me2Al)(μ-O2C)2-1...

A novel family of tetraaza macrocyclic Cu(II) complexes [CuLX(2)] (where L = N(4) donor macrocyclic ligands) and (X = Cl(-), NO(3) (-)) have been synthesized and characterized by elemental analysis, magnetic moments, IR, EPR, mass, electronic spectra and thermal studies. The magnetic moments and electronic spectral studies suggest square planar geometry for [Cu(DBACDT)]Cl(2) and [Cu(DBACDT)](NO...