PURPOSE The purpose of this study was to evaluate the efficacy of retroperitoneal laparoscopic ureterolithotomy for the management of large proximal ureteric stones and the impact of this treatment on postoperative renal function. METHODS The data of 12 patients (7 men and 5 women; mean age, 68.5 ± 8.9 years) with large pyeloureteral junction (2 cases) and upper ureteral (10 cases) stones (25...

BACKGROUND Renal scintigraphy using 99mTc-mercaptoacetyltriglycine (99mTc-MAG3) is widely used for the assessment of renal function in humans. However, the application of this method to animal models of renal disease is currently limited, especially in rodents. Here, we have applied 99mTc-MAG3 renal scintigraphy to a mouse model of unilateral ureteral obstruction (UUO) and evaluated its utility...

abstract background: screening for patients at risk of renal scarring is a challenge in children with acute pyelonephritis (apn). diuretic tc-99m mercaptoacetyltriglycine (mag3) scintigraphy with zero time injection of furosemide (mag3-f0) was observed to display focal parenchymal disorders. the advantages of mag3 include: lower radiation dose and short duration of the test. the aim of this stu...

OBJECTIVE Since the approval of mercaptoacetyltriglycine (MAG3) for routine clinical use, reports have appeared about hepatobiliary excretion deleteriously affecting available diagnostic and quantitative information. The purpose of this study was to evaluate gallbladder (GB) uptake of MAG3 in the clinical setting and its effect on the evaluation of relative renal function and imaging. METHODS...

Objectives: We have previously developed a renal expert system (RENEX) as a decision support tool to assist in the interpretation of Tc-99m MAG3 scans to detect renal obstruction in patients referred for diuresis renography. A decision support system may give the right answer for the wrong reasons. This study is to describe and evaluate a software engine to justify the conclusions reached by RE...

Previous studies have suggested that by slight modification of the cu"entformulosfor iodine-131 (1) orthoiodohippurate (OIH) effective renal plasma flow (ERPF) quantitation, technetium99m ('mTc) mercaptoacetyltriglycine (MAG~ can be substituted for 1-0IH in the quantitative renal function protocol. This study was undertaken to compare two different camera techniques that do not require blood sa...

UNLABELLED High kidney radiation doses during clinical peptide receptor radionuclide therapy (PRRT) with β-particle-emitting radiolabeled somatostatin analogs will lead to renal failure several months after treatment, urging the coinfusion of the cationic amino acids lysine and arginine to reduce the renal radiation dose. In rat PRRT studies, renal protection by the coadministration of lysine w...

TO THE EDITOR: We read with much interest the paper published by Garcia et al. (1) on an expert system for the diagnosis of renal obstruction using 99mTc-mercaptoacetytriglycine (MAG3) renography. Providing that an acceptable gold standard exists, a validated expert system may help an inexperienced observer in daily clinical work. Unfortunately, the diagnosis of renal obstruction is a matter of...