BACKGROUND AND PURPOSE The suture middle cerebral artery occlusion (MCAO) model is widely used for the simulation of focal cerebral ischemia in rats. This technique causes hypothalamic injury resulting in hyperthermia, which can worsen outcome and obscure neuroprotective effects. Herein, we introduce a new MCAO model that avoids these disadvantages. METHODS Permanent MCAO was performed by int...

BACKGROUND Ultrasound induced hyperthermia is a useful adjuvant to radiation therapy in the treatment of prostate cancer. A uniform thermal dose (43 degrees C for 30 minutes) is required within the targeted cancerous volume for effective therapy. This requires specific ultrasound phased array design and appropriate thermometry method. Inhomogeneous, acoustical, three-dimensional (3D) prostate m...

The focus of this review is on the physical and magnetic properties that are related to efficiency monometallic nanoparticles used in biomedical applications, such as resonance imaging (MRI) or nanoparticle hyperthermia, how model these by theoretical methods, where discussion based example cobalt nanoparticles. Different simulation systems (cluster, extended slab, models) critically appraised ...

OBJECTIVE The objective was to establish a pattern of tumor growth of the C6 model of glioblastoma multiform in Wistar rats via magnetic resonance imaging (MRI) for the subsequent verification of tumor volume reduction due to magnetic hyperthermia therapy. METHODS Young male Wistar rats weighing between 250 and 300 g were used for the C6 model. After the rats were anesthetized (55 mg/ kg keta...

Magnetic nanoparticles offer some attractive possibilities in biomedicine because it has the special physical properties. Magnetic hyperthermia using magnetic nanoparticles requires that the magnetic particles have not only high heating ability in low magnetic field but also to be non-toxic for biomedical use. Although the reports of bulk magnetic materials or Fe3O4 nanoparticles have known for...

Magnetic resonance imaging (MRI) scanners have recently been used for magnetic actuation of robots minimally invasive medical operations. Due to MRI's high soft-tissue selectivity, it is possible obtain 3D images hard-to-reach cavities in the human body, where wireless miniature powered by MRI could be employed high-precision targeted operations, such as drug delivery, stem cell therapy, and hy...

PURPOSE This study tests whether dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters obtained from canine patients with soft tissue sarcomas, treated with hyperthermia and radiotherapy, are predictive of therapeutic outcome. EXPERIMENTAL DESIGN Thirty-seven dogs with soft tissue sarcomas had DCE-MRI done before and following the first hyperthermia. Signal enhancement for...

This review article presents an overview of the role magnetic nanoparticles (MNPs) in various biomedical applications. Various synthesis techniques have been discussed compliance with their suitability biological Utilizing property nanoparticles, several technology applications developed such as resonance imaging (MRI), separation biomolecules, biosensing, bacteria inhibition, field stimulated ...

Magnetic fluid hyperthermia as a cancer treatment method is an attractive alternative to other forms of hyperthermia. It is based on the heat released by magnetic nanoparticles subjected to an alternating magnetic field. Recent studies have shown that magnetic fluid hyperthermia-treated cells respond significantly better to chemotherapeutic treatment compared with cells treated with hot water h...

The popularity of patch antennas in magnetic resonance imaging (MRI) has reduced because the large size required for antennae to resonate. Since antenna is associated with wavelength and wavelengths that are used MRI substantially large, used. Methods reducing sizes have been proposed; however, these methods reduce penetration depth uniformity. In this study, we area by 30% folding ground plane...