background there are different and controversial reports about zinc deficiency in patients with major thalassemia. objectives the aim of this study was to evaluate zinc status in patients with major thalassemia in sistan and baluchistan province, southeastern iran. patients and methods the study was performed in ali asghar hospital, a specialized governmental hospital located in zahedan, iran. ...

β- thalassemia major is a common hemoglobinopathy in humans. in some journals, numerous studies have reported different prevalence of hepatitis c among β- thalassemia major because thalassemic patients need multiple blood transfusions and blood transfusion is a common transmission pathway for hepatitis c virus. thus this study was performed for detection of anti-hcv between β- thalassemia major...

background: the reproductive and sexual health issues concerning persons affected by thalassemia major are complex. the study was planned to investigate the psychological attitudes and expectations in a group of thalassemic pregnant women attending hospital for regular blood transfusion. methods : this is a preliminary cross-sectional study involving 20 consecutive thalassemic patients and a co...

abstract background iron overload is a major problem in patients with major thalassemia. an effective and safe iron chelator protocol with high compliance rate plays an important role in treatment of these patients. this study was done to assess the efficacy and safety of the sequential deferoxamine and deferasirox protocol in major thalassemia patients in khuzestan province, iran. material and...

Suntaree Apibal, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400 (Thailand) The presence of fetal red cells (F cells) in the maternal circulation is an indicator of a fetomaternal hemorrhage which may subsequently lead to hemo-lytic disease of the newborn [1]. However, a small amount of F cells were found in some normal adults [4] whereas the increase in hemogl...

aid in the analysis of data, and (c) the interpretation of results in a biomedically meaningful manner.1 To fulfill these aims, vast amounts of information are stored in information repositories called databases. Database types differ considerably depending, primarily, on the nature of the information stored. In biomedical applications, the hierarchical and relational schemes are widely used. A...

introduction: hypoparathyroidism (hpt) is an irreversible but preventable disorder caused by an iron overload which can be considered a typical complication in patients with beta-thalassemia major. patients and method: parathyroid function was evaluated in 130 patients in qom, iran, who suffered from beta-thalassemia major. their serum ferritin levels were checked for monitoring of chelation th...

background: thalassemia syndromes are the most prevalent single gene disorders in iran. this study aimed to evaluate the effect of different types of beta-globin gene mutations, co-inheritance of alpha-globin gene mutations and/or xmn1 snp on disease phenotype in a large cohort of iranian patients. subjects and methods: in total, 433 patients were clinically classified into β-thalassemia major ...