Antidepressants are efficacious for pediatric major depressive disorder, obsessive compulsive disorder (OCD), and non-OCD anxiety disorders. Antidepressants should be used in an evidence-based fashion, with frequent monitoring for side effects, especially when initiating treatment and adjusting dosage. With diligence to appropriate prescribing and monitoring, the benefits of therapy outweigh th...

objective: major depressive disorder is a severe disorder that has a significant impact on the psychological and social functioning of children and adolescents. considering current limitations in the treatment of this disorder, the present study was performed to evaluate the efficacy of fluvoxamine in the treatment of children and adolescents with major depressive disorder. method: in an open t...

objective: suicide is one of the most important early causes of death in psychotic patients. the main object of this research was to determine the relationship between positive and negative symptoms of schizophrenia and psychotic major depressive disorder (mdd) with suicidal history and risk. methods: sixty five patients with schizophrenia compared to 65 patients with psychotic mdd in a cross s...

objective: numerous iranian veterans who took part in iraq-iran war have developed post traumatic stress disorder (ptsd). several studies demonstrated changes in serum lipid concentrations in chronic ptsd (cptsd) patients. the purpose of this study was to assess serum lipid concentrations in soldiers with cptsd and compare it with serum lipid concentrations in patients with chronic mdd (cmdd). ...

OBJECTIVE To examine the impact of psychiatric comorbidity on cognitive-behavioral therapy response in children and adolescents with obsessive-compulsive disorder. METHOD Ninety-six youths with obsessive-compulsive disorder (range 7-19 years) received 14 sessions of weekly or intensive family-based cognitive-behavioral therapy. Assessments were conducted before and after treatment. Primary ou...

Postpartum major depression is a disorder that is often unrecognized and must be distinguished from "baby blues." Antenatal depressive symptoms, a history of major depressive disorder, or previous postpartum major depression significantly increase the risk of postpartum major depression. Screening with the Edinburgh Postnatal Depression Scale may be appropriate. Some women with postpartum major...

OBJECTIVE Serotonin reuptake inhibitor (SRI) medications are effective in the treatment of both major depressive disorder and obsessive-compulsive disorder (OCD), but it is unknown whether the neural substrates of treatment response for the two disorders are the same or different. The authors sought to identify pretreatment cerebral glucose metabolic markers of responsiveness to SRI treatment i...

objective: the present research aims to analyze the efficacy of group metacognitive therapy (mct) on selfesteem and mental health of those who suffer from major depressive disorder. methods: the research was a randomized clinical controlled trial, using pretest and posttest with 2 months of follow-up. twenty-two patients with major depressive disorder based on dsm-iv-tr criteria were selected t...

major depressive disorder (mdd) is one of the most common psychiatric disorders which affects married couples frequently.the present study aims to explain the role of family processes, social support and demographic factors in marital satisfaction of women with major depressive disorder (mdd).in this cross-sectional study, 188 women with mdd were randomly selected among the patients who visited...

aim and background:  major depressive disorder (mdd) has physically and psychological effect on individuals with that disorder. one of the effective areas is emotion expression styles and metacognitive beliefs that has important role in interpersonal and between individual relationships. the purpose of this research was study of emotion expression styles and metacognitive beliefs in individuals...