malignant mixed germ cell tumors,though rare overall, are the most common type of malignant ovarian neoplasms in young and adolescent girls. these tumors are rapidly growing and can metastasize. we report a case of 13-yr-old girl who presented at shkm gmc, nalhar, mewat, haryana, india in december 2013 with huge abdominal lump of a malignant mixed germ cell tumor comprising both immature terato...

Mel-CAM (previously MUC18) is an integral membrane glycoprotein involved in heterophilic intercellular adhesions. Mel-CAM is expressed specifically in certain normal mesenchymal tissues, including smooth muscle, endothelium, and Schwann cells. As a member of the immunoglobulin supergene family of cell adhesion molecules (CAMs), Mel-CAM may play a pivotal role in the normal differentiation and f...

we describe a case of pulmonary blastoma, a rare primary lung malignancy which affects a younger population. this tumor contains both mesenchymal and epithelial elements. pulmonary blastoma tends to relapse locally and metastasizes mainly in the first few years. it has a poor 5-year prognosis, and shows a potentid radio-chemosensitivity. because these tumors are considered malignant, surgical e...

SUMMARY Occurance of Malignant Fihrous Histiocytoma (MFH) of the spermatic cord as a primary source is so rare that since I 967 Just 12 of such cases have heen reported (4,8, 10). MFH is one of the pleomorphic soft tissue Malignant tumors which has been studied for first time by Ozzello and Co workers on 1963. The Tumor ong1nates from primary Mesenchymal cells which have both histocytic & fi...

Carcino-sarcoma is a malignant mixed mesodermal neoplasm accounting for less than 1% of all ovarian tumors. It an aggressive tumor, composed both epithelial and mesenchymal components. To the best our knowledge, 400 cases carcino-sarcomas have been reported in literature only 10% them are bilateral. In this paper, we report new case unilateral carcino-sarcoma 20-year-old adolescent girl with ai...

Abstract Synovial sarcomas are rare malignant mesenchymal soft tissue tumors. We presented the case of a 53-year-old woman patient presenting with acute deep vein thrombosis, later diagnosed as synovial sarcoma femoral wall. The tumor was identified through cross-sectional magnetic resonance angiography and computed tomography, followed by ultrasound-guided core biopsy. report emphasized import...

Aims: Strong expression of CD 34 has been described in many tumors. It has been proposed that these lesions arise from long-lived mesenchymal cells. We tested the hypothesis that spindle cell lesions of the breast arise from similar mesenchymal cells in mammary stroma, and to determine the potential diagnostic value of CD 34 immunostaining in these lesions. Methods and results: Sections of fibr...

Mammary sarcomas are uncommon tumors. Of these pure chondrosarcoma without any other area of epithelial or mesenchymal differentiation feature as even rarer. This excludes tumors like malignant cystosarcoma phyllodes and metaplastic carcinoma where malignant cartilaginous areas may be present. Further primary chondrosarcoma arises from breast stroma and not from underlying bone or cartilage. On...

Pulmonary chondroid hamartomas (PCH) are biphasic benign tumors that contain both mesenchymal and epithelial populations. In this report we describe two PCH in which clonal translocations at chromosome band 6p21 were demonstrated in mesenchymal cells. One of these had a unique translocation, t(6;14)(p21;q24), that was also found in one of two PCH karyotyped previously. The t(6;14) has not been ...